A re-evaluation of the risk of microbial keratitis from overnight contact lens wear compared with other life risks.
A re-evaluation of the risk of microbial keratitis from overnight contact lens wear compared with other life risks.
复制标题
与其他生活风险相比，重新评估过夜佩戴隐形眼镜引起的微生物性角膜炎的风险。
DOI：
10.1097/icl.0b013e3181998dd3
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Diaz,Mireya
中科院分区：
文献类型：
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作者：
Szczotka-Flynn,Loretta;Ahmadian,Rouzbeh;Diaz,Mireya
目的：1995年，Myers和韦斯发表了一篇文章，比较了与低透氧性（Dk）长期接触透镜配戴相关的溃疡性角膜炎风险与其他生命风险。本文更新了与硅水凝胶（SH）长戴型接触透镜使用相关的风险和一些比较生命风险，以提供当前生命风险等级内的观点。方法：比较比率定义为SH长戴型接触透镜使用者人群中微生物角膜炎的发生率除以给定风险人群中其他疾病或事件的发生率。结果：SH镜片相关的微生物角膜炎的风险比一般人群中某些非致命性破坏性事件的风险低约1.5至16倍，和患乳腺癌的风险差不多。与其他眼部疾病相比，SH镜片的微生物角膜炎风险与白内障摘除术后每年发生晚期年龄相关性黄斑变性或视网膜脱离的风险大致相同;它比发生眼睛或眼眶癌的风险高200倍以上;它比圆锥角膜中进行穿透性角膜移植、发展成核性白内障结论：尽管现代SH接触透镜长期配戴的微生物角膜炎风险自20世纪80年代以来没有改变，但与其他生命风险相比，这是一种相对罕见的事件。
Purpose:In 1995, Myers and Weiss published an article comparing the risk of ulcerative keratitis related to low oxygen permeability (Dk) extended contact lens wear to other life risks. This article updates the risks associated with silicone hydrogel (SH) extended wear contact lens use and some comparative life risks, to provide a current perspective within the hierarchy of life risks.Methods:A comparative ratio was defined as the incidence of microbial keratitis in a population of SH extended wear contact lens users divided by the incidence of other disease or occurrence in a given population at risk.Results:The risk of SH lens-related microbial keratitis is about 1.5 to 16 times less risky than certain nonfatal disruptive occurrences in the general population, and about the same as the risk of developing breast cancer. Compared with other ocular conditions, the risk of microbial keratitis with SH lenses is about the same as developing late-stage age-related macular degeneration or retinal detachment after cataract extraction on an annual basis; it is over 200 times greater than developing eye or orbit cancer; it is about 7, 20, or more than 30 times less than proceeding to penetrating keratoplasty in keratoconus, developing nuclear cataract, or experiencing a corneal inflammatory event during low-Dk extended wear, respectively.Conclusions:Although the risk of microbial keratitis with modern day SH contact lens extended wear has not changed since the 1980s, when put in perspective with other life risks, it is a relatively rare occurrence.