Melanins and melanosomes from llama (Lama glama L.)
Melanins and melanosomes from llama (Lama glama L.)
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DOI：
10.1111/j.1600-0749.2004.00139.x
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发表时间：
2004-06-01
期刊：
影响因子：
--
通讯作者：
Renieri, C
中科院分区：
文献类型：
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作者：
Cecchi, T;Cozzali, C;Renieri, C
8只成年有色阿根廷大羊驼毛发和皮肤中黑色素和黑素体的分析已经实施了。在每个样本中，都鉴定出真黑素、黑素和碱溶黑素。黑色素的总量和真黑素的数量都从黑色下降到红棕色，而在每个样本中都发现了少量的黑色素。真核小体呈圆形、椭圆形，低倍镜下可见清晰的横纹。深褐色样本显示了所有四个黑素小体阶段。I期和II期黑素小体表现为大的、不对称的空泡，其中含有大量随机散布在无定形蛋白物质(囊泡球状小体)中的微泡。III期黑素小体在微泡和基质中有微粒状黑色素沉积。完全黑化的黑素小体(IV期)以圆形为主，轮廓不规则，电子致密的色素排列成大簇。在浅褐色黑素细胞中，可见不同成熟阶段的大量黑素小体。前黑素小体呈卵圆形，内含无定形蛋白物质和点状、微粒状沉积物。成熟的黑素小体是完全黑化的，均匀的电子致密，卵圆形颗粒。
Analysis of melanins and melanosomes in eight hair and skin samples taken of adult pigmented Argentine llamas (Lama glama L.) has been carried out. In each sample, eumelanins, pheomelanins and alkali-soluble melanins were identified. The total amount of melanins and the amount of eumelanins both decreased from black to reddish brown colour, while pheomelanins were found to be present in small quantities in each sample. Eumelanosomes were round and oval-shaped, displaying transverse striations clearly visible at low magnification. Dark brown samples revealed all four melanosomes stages. Stages I and II melanosomes appeared as large, asymmetrical vacuoles containing numerous microvesicles randomly scattered within an amorphous proteinaceous material (vesiculo-globular bodies). Stage III melanosomes had microgranular melanin deposits in the microvesicles and in the matrix. The fully melanized melanosomes (stage IV) were primarily round-shaped, showing an irregular outline and the electron-dense pigment was arranged to form large clusters. In light brown melanocytes, numerous melanosomes at different maturation stages could be found. Premelanosomes appeared ovoid, containing amorphous proteinaceous material and spotty and microgranular deposits. Mature melanosomes were fully melanized, homogeneously electron-dense, ovoid granules.