Hepatic resection of metastatic colorectal carcinoma: a ten-year experience.

Hepatic resection of metastatic colorectal carcinoma: a ten-year experience.
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转移性结直肠癌肝切除:十年经验。

DOI:
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发表时间:
1982
影响因子:
--
通讯作者:
W. Longmire
W. Longmire
中科院分区:
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文献类型:
--
作者:
S. E. Logan;S. Meier;K. Ramming;D. Morton;W. Longmire

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在过去的十年中,19例患者在UCLA接受了转移性结直肠癌的部分肝切除术,包括5例三肝段切除术(TS),8例肺叶切除术(L)和6例肝段切除术(SG),仅1例(5.3%)死亡。12个病灶为单发(S),7个为多发(M)。平均生存期为27.4个月,3名患者生存超过5年,1名患者生存近8年。S存在更好的平均生存期(33.2个月)与M相比(15.8个月)病变;对于较小切除:SG(44.7个月),与L(24.3个月)和TS(11.0个月);对于延迟出现肝转移的患者:两年以上(40.5个月)、一年以下(24.8个月)和同步(23.1个月)。存活率应该有所提高,因为12名存活患者中没有一人有复发疾病的证据,许多人的随访时间很短。这一经验为可切除的结直肠癌肝转移的积极手术治疗辩护,因为全身治疗效果明显较差。
Nineteen patients have undergone partial hepatectomy for metastatic colorectal carcinoma at UCLA during the past ten years, including five trisegmentectomies (TS), eight lobectomies (L), and six segmentectomies (SG), with only one (5.3%) mortality. Twelve lesions were solitary (S) and seven multiple (M). Mean survival is 27.4 months, with three patients surviving over five years and one nearly eight years. Better mean survival exists for S (33.2 months) compared with M (15.8 months) lesions; for lesser resections: SG (44.7 months), compared with L (24.3 months) and TS (11.0 months); and for those with delayed appearance of hepatic metastases: beyond two years (40.5 months), less than one year (24.8 months), and synchronous (23.1 months). Survival figures should improve, as none of the 12 surviving patients have evidence of recurrent disease and many have short follow-up. This experience defends aggressive surgical treatment of resectable colorectal carcinoma metastatic to liver, because systemic therapy is markedly less effective.
右三段切除术治疗肝肿瘤。
DOI: --
发表时间: 1980
期刊: Surgery, gynecology & obstetrics
影响因子: --
作者:
Starzl,TE;Koep,LJ;Weil3rd,R;Lilly,JR;Putnam,CW;Aldrete,JA
通讯作者: Aldrete,JA