Erythema Multiforme-Like Bullous Pemphigoid Associated with Furosemide
Erythema Multiforme-Like Bullous Pemphigoid Associated with Furosemide
复制标题
速尿相关的多形红斑样大疱性类天疱疮
DOI：
10.4172/2155-9554.1000123
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
A. Hood
中科院分区：
文献类型：
--
作者：
Stefanie A. Hirano;A. Mason;V. Harvey;A. Hood
大疱性类天疱疮（BP）的临床诊断具有挑战性，因为这种疾病具有多形性。我们提出一例多形性红斑（EM）样BP在一个80岁的妇女乳糜泻。皮肤活检显示表皮内和表皮下大泡，直接免疫荧光（DIF）显示IgG和C3在基底膜呈线性沉积。本例患者血压的病因尚不清楚，但可能与使用速尿有关，并与乳糜泻发作有关。据我们所知，只有其他四个已发表的病例记录了BP的em样病变。BP的不典型表现应通过组织学和直接免疫荧光证实。
The clinical diagnosis of bullous pemphigoid (BP) can be challenging given the polymorphic nature of the disease. We present a case of erythema multiforme (EM)-like BP in an 80-year-old woman with celiac disease. Skin biopsies showed intraepidermal and subepidermal bullae with direct immunofluorescence (DIF) demonstrating IgG and C3 linear deposition at the basement membrane. The etiology of our patient's BP is unclear but may be associated with furosemide usage and is temporally associated with a flare of celiac sprue. To our knowledge, only four other published cases document EM-like lesions in BP. Atypical presentations of BP should be confirmed with histology and direct immunofluorescence.