MAMMOGRAPHIC PARENCHYMAL PATTERNS AND BREAST-CANCER RISK
MAMMOGRAPHIC PARENCHYMAL PATTERNS AND BREAST-CANCER RISK
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DOI：
10.1093/oxfordjournals.epirev.a036300
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发表时间：
1987-01-01
影响因子：
5.5
通讯作者：
SZKLO, M
中科院分区：
文献类型：
--
作者：
SAFTLAS, AF;SZKLO, M
The literature on cancer of the female breast is vast and has succeeded in identifying a number of risk factors for the disease. Recognized breast cancer risk factors as a group, however, can account for only a small percentage of the diagnosed cases (1). As yet, there are no prescribed measures that a woman can employ to prevent the occurrence of breast cancer; early detection remains the most effective means of reducing breast cancer morbidity and mortality. From studies by the Health Insurance Plan of New York (2) and the Swedish National Board of Health and Welfare (3), as well as from findings by the Breast Cancer Detection and Demonstration Projects screening program (4), mammography is now recognized as the most sensitive screening modality for the detection of nonpalpable and minimal breast cancers, particularly among women aged 50 years and older. The ability to define women at high risk of developing breast cancer would reinforce and possibly enhance breast cancer screening efforts. In 1976, Wolfe first proposed mammographic parenchymal patterns as indicators for predicting the risk of breast cancer (5, 6), postulating that four patterns—Nl, PI, P2, and DY—were associated with a stepwise increase in breast cancer risk. His initial studies found high risks of breast cancer associated with the P2 and DY parenchymal patterns.
