Enhanced efficacy of amphotericin B and rifampicin combined in treatment of murine histoplasmosis and blastomycosis.

Enhanced efficacy of amphotericin B and rifampicin combined in treatment of murine histoplasmosis and blastomycosis.
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两性霉素B与利福平联合治疗小鼠组织胞浆菌病和芽生菌病疗效增强。

DOI:
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发表时间:
1976
影响因子:
6.4
通讯作者:
G. Medoff
G. Medoff
中科院分区:
医学2区
文献类型:
--
作者:
M. Kitahara;G. Kobayashi;G. Medoff

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两性霉素 B 与利福平联合治疗鼠组织胞浆菌病和芽生菌病比单独使用任一药物更有效。治疗效果的增加并不伴随着毒性的增加。
Amphotericin B in combination with rifampicin was more effective in the treatment of murine histoplasmosis and blastomycosis than either agent alone. The increased therapeutic effects were not accompanied by an increase in toxicity.