Quantitative analysis of peptides and proteins in biomedicine by targeted mass spectrometry.

Quantitative analysis of peptides and proteins in biomedicine by targeted mass spectrometry.
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DOI:
10.1038/nmeth.2309
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发表时间:
2013-01
期刊:
影响因子:
48
通讯作者:
Carr, Steven A.
Carr, Steven A.
中科院分区:
生物学1区
文献类型:
--
作者:
Gillette, Michael A.;Carr, Steven A.

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Targeted mass spectrometry (MS) is becoming widely used in academia and in pharmaceutical and biotechnology industries for sensitive and quantitative detection of proteins, peptides and post-translational modifications. Here we describe the increasing importance of targeted MS technologies in clinical proteomics and the potential key roles these techniques will have in bridging biomedical discovery and clinical implementation.
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