Spatial differences and temporal changes in illicit drug use in Europe quantified by wastewater analysis
Spatial differences and temporal changes in illicit drug use in Europe quantified by wastewater analysis
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DOI：
10.1111/add.12570
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发表时间：
2014-08-01
期刊：
影响因子：
6
通讯作者：
Thomas, Kevin V.
中科院分区：
文献类型：
--
作者：
Ort, Christoph;van Nuijs, Alexander L. N.;Thomas, Kevin V.
目的进行废水分析，以评估空间差异和时间变化的非法药物使用在一个大的欧洲人口。2012年和2013年为期一周的原废水设计分析。欧洲各地污水处理厂（WWTPs）的集水区如下：2012年：11个国家（23个城市，总人口1150万）的25个WWTPs; 2013年：21个国家（42个城市，总人口2474万）的47个WWTPs。使用基于液相色谱-质谱联用的方法对废水样品中五种非法药物（可卡因、苯丙胺、摇头丸、甲基苯丙胺、大麻）的排泄产物进行了定量。结果空间差异进行了评估，并确认在欧洲大都市地区有很大的不同。总体而言，结果与现有的传统监测数据一致。虽然在个别城市和年份的时间变化很大（P范围从微不足道到
Aims To perform wastewater analyses to assess spatial differences and temporal changes of illicit drug use in a large European population. Design Analyses of raw wastewater over a 1-week period in 2012 and 2013. Setting and Participants Catchment areas of wastewater treatment plants (WWTPs) across Europe, as follows: 2012: 25 WWTPs in 11 countries (23 cities, total population 11.50 million); 2013: 47 WWTPs in 21 countries (42 cities, total population 24.74 million). Measurements Excretion products of five illicit drugs (cocaine, amphetamine, ecstasy, methamphetamine, cannabis) were quantified in wastewater samples using methods based on liquid chromatography coupled to mass spectrometry. Findings Spatial differences were assessed and confirmed to vary greatly across European metropolitan areas. In general, results were in agreement with traditional surveillance data, where available. While temporal changes were substantial in individual cities and years (P ranging from insignificant to