Fiber optic direct Raman imaging system based on a hollow-core fiber bundle
Fiber optic direct Raman imaging system based on a hollow-core fiber bundle
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DOI：
10.1117/12.2078662
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发表时间：
2015-03
期刊：
影响因子：
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通讯作者：
S. Inoue;T. Katagiri;Y. Matsuura
中科院分区：
文献类型：
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作者：
S. Inoue;T. Katagiri;Y. Matsuura
将中空纤维束和直接成像技术相结合，构建了一种用于高速内窥镜拉曼成像的拉曼成像系统。中空纤维束是通过在预拉伸玻璃毛细管束的内表面沉积一层银薄膜而制成的。它作为光纤探头传输高信噪比的拉曼图像，因为传播的光被限制在空气芯中，导致很少的光散射。激发激光通过探头均匀照射样品上的视场。背向散射图像由探头采集，并由图像传感器直接捕获。使用一对薄膜可调谐滤光片来选择目标拉曼波段。该成像系统能够对生物组织进行灵活、高速的拉曼成像。
A Raman imaging system which combined a hollow fiber bundle and a direct imaging technique was constructed for high-speed endoscopic Raman imaging. The hollow fiber bundle is fabricated by depositing a silver thin film on the inner surface of pre-drawn glass capillary bundle. It performs as a fiber optic probe which transmits a Raman image with high signal-to-noise ratio because the propagating light is confined into the air core inducing little light scattering. The field of view on the sample is uniformly irradiated by the excitation laser light via the probe. The back-scattered image is collected by the probe and captured directly by an image sensor. A pair of thin film tunable filters is used to select target Raman band. This imaging system enables flexible and high-speed Raman imaging of biological tissues.