Psychophysiology in the Study of Psychological Trauma: Where Are We Now and Where Do We Need to Be?
Psychophysiology in the Study of Psychological Trauma: Where Are We Now and Where Do We Need to Be?
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DOI：
10.1007/7854_2014_346
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发表时间：
2014-01-01
期刊：
影响因子：
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通讯作者：
Risbrough, V. B.
中科院分区：
文献类型：
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作者：
Acheson, D. T.;Geyer, M. A.;Risbrough, V. B.
创伤后应激障碍（PTSD）是一个主要的公共卫生问题，最近受到越来越多的关注，部分原因是伊拉克和阿富汗的战争。从历史上看，试图了解PTSD的病因和治疗的研究经常使用唤醒的心理生理学测量，因为它们在提供客观，非自我报告的结果方面提供了许多优势，这些结果与拟议的神经生物学机制密切相关，并为跨物种翻译提供了机会。此外，美国国家精神卫生研究所（NIMH）研究领域标准项目（RDoC）中概述的基于症状群的精神疾病分类正在向特定的生物，生理和行为结构转变，这预示着心理生理学研究将继续在创伤相关疾病的研究中发挥重要作用。本文综述了心理生理学措施和PTSD的知识现状，重点是与当前PTSD症状相关的生理标志物，以及被认为与PTSD病理学相关的结构标志物（安全信号学习，恐惧消退），以及创伤后发展PTSD风险的心理生理学标志物。未来的方向和问题的创伤，包括创伤性脑损伤（TBI），治疗结果的研究，和新的可穿戴生理监测技术进行了讨论。
Posttraumatic stress disorder (PTSD) is a major public health concern, which has been seeing increased recent attention partly due to the wars in Iraq and Afghanistan. Historically, research attempting to understand the etiology and treatment of PTSD has made frequent use of psychophysiological measures of arousal as they provide a number of advantages in providing objective, non-self-report outcomes that are closely related to proposed neurobiological mechanisms and provide opportunity for cross-species translation. Further, the ongoing shift in classification of psychiatric illness based on symptom clusters to specific biological, physiological, and behavioral constructs, as outlined in the US National Institute of Mental Health (NIMH) Research Domain Criteria project (RDoC), promises that psychophysiological research will continue to play a prominent role in research on trauma-related illnesses. This review focuses on the current state of the knowledge regarding psychophysiological measures and PTSD with a focus on physiological markers associated with current PTSD symptoms, as well as markers of constructs thought to be relevant to PTSD symptomatology (safety signal learning, fear extinction), and psychophysiological markers of risk for developing PTSD following trauma. Future directions and issues for the psychophysiological study of trauma including traumatic brain injury (TBI), treatment outcome studies, and new wearable physiological monitoring technologies are also discussed.