GABA immunoreactivity in the retina.
GABA immunoreactivity in the retina.
复制标题
视网膜中的 GABA 免疫反应。
DOI：
10.1101/2020.04.10.036012
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发表时间：
1986
影响因子：
4.4
通讯作者：
J. Storm
中科院分区：
文献类型：
--
作者：
E. Agardh;A. Bruun;B. Ehinger;J. Storm
假定的GABA神经元进行了研究，在鸡，豚鼠和兔视网膜的免疫组化程序，旨在直接证明内源性GABA。在所有的物种中，一个子集的无长突细胞的免疫反应，以及众多的纤维内丛状层。在鸡，免疫反应性也表现在水平细胞，和单细胞过程中可以区分两个丛状层。本研究表明，GABA能神经元内的内源性GABA贮存可以用免疫组织化学技术显示。因此，这种直接的方法提供了额外的信息，并且可能比证明与GABA合成和代谢相关的酶更少受到非特异性染色的影响。与目前用于显示GABA神经元的放射自显影技术相比，它还提供了上级分辨率。Invest Ophthalmol维斯科学27：674-678，1986。
Presumed GABA neurons were studied in chick, guinea pig, and rabbit retinae with an immunohistochemical procedure aimed at direct demonstration of the endogenous GABA. In all species, a subset of amacrine cells was immunoreactive, as well as numerous fibers in the inner plexiform layer. In the chick, immunoreactivity was also demonstrated in horizontal cells, and single cell processes could be distinguished in both plexiform layers. The study indicates that the endogenous stores of GABA in GABAergic neurons can be visualized with immunohistochemical techniques. This direct approach thus gives additional information and probably is less subject to nonspecific staining than the demonstration of enzymes linked to GABA synthesis and metabolism. It also gives superior resolution in comparison with the autoradiographic techniques currently used for demonstrating GABA neurons. Invest Ophthalmol Vis Sci 27:674-678, 1986.
GABA 类似物 3H-蝇蕈醇在金鱼和鸡的视网膜中的结合和摄取。
影响因子：
4.4
作者：
Yazulla,S;Brecha,N
通讯作者：
Brecha,N