Nucleation Kinetics and Growth Model of Penicillin Sulfoxide in Butyl Acetate
Nucleation Kinetics and Growth Model of Penicillin Sulfoxide in Butyl Acetate
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DOI：
10.1002/ceat.201200731
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发表时间：
2013-10
影响因子：
2.1
通讯作者：
Dingding Jing;Jinxiu Wang;Ming Zhang;Yaquan Wang;C. Xie
中科院分区：
文献类型：
--
作者：
Dingding Jing;Jinxiu Wang;Ming Zhang;Yaquan Wang;C. Xie
研究了青霉素亚砜在乙酸丁酯中的成核动力学和生长模型。计算了单位体积能、临界核半径、临界自由能垒和形核率等形核参数。在诱导期研究中，选择了一种激光方法来检测第一个晶体。利用扫描电子显微镜和表面熵因子，确定了由乙酸丁酯生成青霉素亚砜的生长模型。
Nucleation kinetics and a growth model of penicillin sulfoxide in butyl acetate were studied. Nucleation parameters such as energy per unit volume, radius of critical nucleus, critical free energy barrier, and nucleation rate were evaluated. A laser method was selected to detect the first crystal in induction period studies. By means of scanning electron microscopy and surface entropy factor, the growth model of penicillin sulfoxide developed from butyl acetate could be determined.