Refractive and Keratometric Stability in High Myopic LASIK With High-Frequency Femtosecond and Excimer Lasers
Refractive and Keratometric Stability in High Myopic LASIK With High-Frequency Femtosecond and Excimer Lasers
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DOI：
10.3928/1081597x-20130924-02
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发表时间：
2013-12-01
影响因子：
2.4
通讯作者：
Asimellis, George
中科院分区：
文献类型：
--
作者：
Kanellopoulos, Anastasios John;Asimellis, George
目的：利用新型飞秒准分子激光手术平台评估高度近视LASIK手术的安全性、有效性、人机工程学以及屈光和角膜稳定性。方法：采用Alcon- waveight FS200飞秒和EX500准分子激光器（Alcon Laboratories, Fort Worth， TX）对160例高度近视LASIK患者（>= -6.00屈光度[D]）进行术前和术后的以下参数评估：屈光不正、矫正距离视力、未矫正距离视力、球面等效矫正、角膜测量（Placido形貌和Scheimpflug断层扫描）和屈光散光。平均随访时间6.2个月（3 ~ 12个月）。结果：术后3个月、6个月和12个月的平均屈光误差分别为-0.37、-0.43和-0.25 D，而术前为-7.67 +/- 1.55 D。术后3、6和12个月，分别有94%、96.3%和100%的眼睛离焦在1.0 D以内。术后3、6、12个月屈光散光分别为-0.21、-0.21、-0.13 D，术前为-1.07 +/- 1.91 D。随访3个月、6个月和12个月时，术后散光在0.25 D以内的眼睛比例分别为85.3%、81.5%和100%。随访12个月后角膜稳定性在0.22 D内。所有病例均未见上皮向内生长或弥漫性板层角膜炎。结论：该技术在高度近视的高水平未矫正视力康复中具有良好的临床效果。在评估的样本中有很小的回归潜力。
PURPOSE: To evaluate safety, efficacy, ergonomy, and refractive and keratometric stability in high myopia LASIK procedures using a novel femtosecond and excimer laser surgery platform.METHODS: One hundred sixteen eyes in consecutive cases of high myopic LASIK (>= -6.00 diopters [D]) with the Alcon-WaveLight FS200 femtosecond and EX500 excimer lasers (Alcon Laboratories, Fort Worth, TX) were evaluated preoperatively and postoperatively for the following parameters: refractive error, corrected distance visual acuity, uncorrected distance visual acuity, spherical equivalent correction, keratometry (with Placido topography and Scheimpflug tomography), and refractive astigmatism. Average follow-up time was 6.2 months (range: 3 to 12 months).RESULTS: Postoperative average refractive error was -0.37, -0.43, and -0.25 D for the 3-, 6-, and 12-month period, compared to -7.67 +/- 1.55 D preoperatively. At 3, 6, and 12 months postoperatively 94%, 96.3%, and 100% of eyes, respectively, were within 1.0 D defocus equivalent. Postoperative refractive astigmatism was -0.21, -0.21, -0.13 D for the 3-, 6-, and 12-month period compared to -1.07 +/- 1.91 D preoperatively. The proportion of eyes with postoperative astigmatism within 0.25 D was 85.3%, 81.5%, and 100%, for the 3-, 6-, and 12-month visit, respectively. Keratometric stability was within 0.22 D after the 12-month visit. There was no epithelial ingrowth or diffuse lamellar keratitis in any case.CONCLUSIONS: Clinical outcomes with this technique and technology appear to be promising in high level uncorrected visual rehabilitation of high myopia. There was small regression potential in the sample evaluated.