OBJECT EXPLORATION IN STAGGERER MUTANT MICE

OBJECT EXPLORATION IN STAGGERER MUTANT MICE
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DOI:
10.1016/0031-9384(87)90139-9
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发表时间:
1987-01-01
影响因子:
2.9
通讯作者:
BOIVIN, D
BOIVIN, D
中科院分区:
医学3区
文献类型:
--
作者:
LALONDE, R;BOTEZ, MI;BOIVIN, D

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人们发现,小脑中失去浦肯野细胞和颗粒细胞的交错突变小鼠比正常小鼠探索放置在熟悉环境中的新物体的时间更长。两组之间的一般运动活动没有差异。这些结果讨论了小脑在行为抑制和情绪中的作用。
Staggerer mutant mice, which lose Purkinje and granule cells in the cerebellum, were found to explore for a longer period of time than normal mice a novel object placed in a familiar environment. There was no difference between the two groups in terms of general motor activity. These results are discussed in regard to a role for the cerebellum in behavioral inhibition and emotion.