Fluoroquinolone-resistant Streptococcus agalactiae: epidemiology and mechanism of resistance.

Fluoroquinolone-resistant Streptococcus agalactiae: epidemiology and mechanism of resistance.
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氟喹诺酮耐药无乳链球菌：流行病学和耐药机制。

DOI：
10.1128/aac.49.6.2495-2497.2005
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发表时间：
2005
期刊：
Antimicrobial agents and chemotherapy.
影响因子：
--
通讯作者：
Rahal,JamesJ
Rahal,JamesJ
中科院分区：
--
文献类型：
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作者：
Wehbeh,Wehbeh;Rojas-Diaz,Roberto;Li,Xinying;Mariano,Noriel;Grenner,Louise;Segal-Maurer,Sorana;Tommasulo,Barbara;Drlica,Karl;Urban,Carl;Rahal,JamesJ

文献摘要

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从单个患者分离株中回收了耐喹诺酮类无乳链球菌，发现其含有旋转酶和拓扑异构酶 IV 基因突变。脉冲场凝胶电泳表明，来自同一长期护理机构的四种分离株密切相关；七例为耐喹诺酮类流感嗜血杆菌和链球菌。从同一患者体内分离出无乳杆菌。
Quinolone-resistantStreptococcus agalactiaebacteria were recovered from single-patient isolates and found to contain mutations in the gyrase and topoisomerase IV genes. Pulsed-field gel electrophoresis demonstrated that four isolates from the same long-term care facility were closely related; in seven cases, quinolone-resistantHaemophilus influenzaeandS. agalactiaebacteria were isolated from the same patient.