Recovery in instrumental activities of daily living (IADLs): findings from the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)
Recovery in instrumental activities of daily living (IADLs): findings from the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)
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DOI：
10.1093/ageing/afp128
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发表时间：
2009-11-01
期刊：
影响因子：
6.7
通讯作者：
Matthews, Fiona E.
中科院分区：
文献类型：
--
作者：
Seidel, David;Jagger, Carol;Matthews, Fiona E.
设计：MRC CFAS从英国的五个社区招募了13，004名年龄在65岁及以上的人。参与者在1990年至1994年期间接受了基线访谈，并在2年后重新评估。参与者：在基线时报告无法在没有困难或帮助的情况下进行任何IADL的参与者（“残疾人”）被纳入分析。使用逻辑回归估计随访时从残疾状态改善为非残疾状态的优势比（OR结果：在基线时，50%的人报告残疾，其中9%的人在随访时报告独立功能。妇女（OR = 0.4）和年龄>= 75岁的参与者（OR = 0.2）最不可能恢复，其次是自评健康状况较差的人（OR = 0.5），使用至少一种药物（OR = 0.6）且有≥ 2种合并症结论：少数参与者在基线时报告残疾，然后在2年时报告独立功能。把重点放在那些一旦残疾似乎最不可能康复的人身上可能很重要。已被证明会增加残疾风险的几个因素与康复呈负相关，这表明干预方案可以针对这些相同的因素。
Design: MRC CFAS recruited a sample of 13,004 individuals aged 65 years and above from five communities in the UK. Participants underwent a baseline interview between 1990 and 1994 and were re-assessed 2 years later.Participants: the participants who reported that they were unable to perform any IADL without difficulty or help at baseline ('disabled') were included in the analysis.Methods: logistic regression was used to estimate odds ratios (OR) for improvement from disabled to non-disabled state at follow-up ('recovery').Results: at baseline, 50% reported disability of whom 9% reported independent function at follow-up. Women (OR = 0.4) and participants aged >= 75 years (OR = 0.2) were least likely to recover, followed by those with poor self-rated health (OR = 0.5), using at least one medication (OR = 0.6) and having more than or equal to two co-morbidities (OR = 0.6).Conclusion: a minority of participants reporting disability at baseline then reported independent function at 2 years. It may be important to focus on those who seem least likely to recover once they have become disabled. Several factors that have been shown to increase the risk of disability were inversely associated with recovery, suggesting that intervention programmes could target these same factors.