Biomechanical and histologic evaluation of the effects of underwater treadmill exercise on horses with experimentally induced osteoarthritis of the middle carpal joint
Biomechanical and histologic evaluation of the effects of underwater treadmill exercise on horses with experimentally induced osteoarthritis of the middle carpal joint
复制标题
DOI：
10.2460/ajvr.78.5.558
复制
发表时间：
2017-05-01
影响因子：
1
通讯作者：
Werpy, Natasha M.
中科院分区：
文献类型：
--
作者：
King, Melissa R.;Haussler, Kevin K.;Werpy, Natasha M.
目的评价水下跑步机(UWT)训练对实验性腕中关节骨性关节炎马匹前肢生物力学和关节组织学结果的影响。从第15天开始，马匹被分配到以相同的速度、频率和持续时间在UWT或无水UWT(模拟受控手部行走)中锻炼。在-7天(基线)、14天、42天和70天收集胸部和骨盆肢体的地面反作用力、胸肢运动学和作用于腕部的部分胸肢肌肉的肌电结果。每周评估包括临床评估跛行、对腕关节屈曲的反应以及胸肢关节的角度测量。在研究结束时，对腕关节中部的关节软骨和滑膜进行了组织学检查。结果与马匹模拟徒手行走的结果相比，在对称的胸肢负荷、选定的胸肢肌肉的均匀激活模式和腕关节屈曲恢复到基线值方面，UWT锻炼显著减少了滑膜炎症，并导致了显著的临床改善。结论：在胸肢功能、关节活动度和滑膜完整性方面的总体改善表明，在UWT中运动是治疗马腕关节骨关节炎的一种潜在的可行的治疗方案。
OBJECTIVETo evaluate the effects of exercise in an underwater treadmill (UWT) on forelimb biomechanics and articular histologic outcomes in horses with experimentally induced osteoarthritis of the middle carpal joint.ANIMALS16 horses.PROCEDURESAn osteochondral fragment was induced arthroscopically (day 0) in 1 middle carpal joint of each horse. Beginning on day 15, horses were assigned to exercise in a UWT or in the UWT without water (simulating controlled hand walking) at the same speed, frequency, and duration. Thoracic and pelvic limb ground reaction forces, thoracic limb kinematics, and electromyographic results for select thoracic limb muscles acting on the carpi were collected on days -7 (baseline), 14, 42, and 70. Weekly evaluations included clinical assessments of lameness, response to carpal joint flexion, and goniometric measurements of thoracic limb articulations. At study conclusion, articular cartilage and synovial membrane from the middle carpal joints was histologically examined.RESULTSExercise in a UWT significantly reduced synovial membrane inflammation and resulted in significant clinical improvements with regard to symmetric thoracic limb loading, uniform activation patterns of select thoracic limb muscles, and return to baseline values for carpal joint flexion, compared with results for horses with simulated hand walking. CONCLUSIONS ANDCLINICAL RELEVANCEOverall improvements in thoracic limb function, joint range of motion, and synovial membrane integrity indicated that exercise in a UWT was a potentially viable therapeutic option for the management of carpal joint osteoarthritis in horses.