Requirement for homologous recombination functions for expression of the mutA mistranslator tRNA-induced mutator phenotype in Escherichia coli.

Requirement for homologous recombination functions for expression of the mutA mistranslator tRNA-induced mutator phenotype in Escherichia coli.
复制标题

在大肠杆菌中表达 mutA 误译子 tRNA 诱导的突变表型需要同源重组功能。

DOI:
10.1128/jb.182.5.1427-1431.2000
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发表时间:
2000
影响因子:
3.2
通讯作者:
Humayun,MZ
Humayun,MZ
中科院分区:
生物学3区
文献类型:
--
作者:
Ren,L;AlMamun,AA;Humayun,MZ

文献摘要

相似文献

大肠杆菌mut突变体表型的表达需要recA、recB、recC、ruvA和ruvC基因,但不需要recD、recF、recO或recR基因。因此,cBCD依赖性同源重组系统是激活mutA细胞中易错DNA聚合酶的信号通路的组成部分。
Expression of theEscherichia coli mutAmutator phenotype requiresrecA,recB,recC,ruvA, andruvCgene, but notrecD,recF,recO, orrecRgenes. Thus, therecBCD-dependent homologous recombination system is a component of the signal pathway that activates an error-prone DNA polymerase inmutAcells.