Therapy for hepatocellular cancer with intrahepatic arterial adriamycin and 5-fluorouracil combined with whole-liver irradiation: a Northern California Oncology Group Study.
Therapy for hepatocellular cancer with intrahepatic arterial adriamycin and 5-fluorouracil combined with whole-liver irradiation: a Northern California Oncology Group Study.
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肝动脉内阿霉素和 5-氟尿嘧啶联合全肝照射治疗肝细胞癌：北加州肿瘤学小组研究。
DOI：
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发表时间：
1979
期刊：
影响因子：
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通讯作者：
T. Phillips
中科院分区：
文献类型：
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作者：
M. Friedman;P. Volberding;M. Cassidy;K. Resser;T. Wasserman;T. Phillips
采用肝动脉化疗联合5-氟尿嘧啶联合全肝放疗治疗肝细胞癌13例。6名患者(46%)客观消退，5名(38%)病情稳定。81%的患者出现症状改善。有反应的患者中位生存期最短为5.0个月。毒性是可以接受的。对于这种特别侵袭性和难治性的癌症，这是一种有效的联合治疗。
Thirteen patients with hepatocellular cancer were treated with intrahepatic arterial Adriamycin and 5-fluorouracil combined with whole-liver irradiation. Six patients (46%) had an objective regression and five (38%) had stable disease. Symptomatic improvement was noted in 81% of the patients. The minimum median survival time was 5.0 months for those patients who responded. Toxicity was acceptable. This is an effective combination for the treatment of this especially aggressive and intractable form of cancer.