Non-Alzheimer's disease amyloidoses of the nervous system.
Non-Alzheimer's disease amyloidoses of the nervous system.
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非阿尔茨海默病神经系统淀粉样变性。
DOI：
10.1097/00019052-199508000-00006
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发表时间：
1995
影响因子：
4.8
通讯作者：
Frangione,B
中科院分区：
文献类型：
--
作者：
Castaño,EM;Frangione,B
淀粉样变性和朊病是蛋白质构象的紊乱。本文综述了淀粉样蛋白形成的一般机制。脑淀粉样蛋白分子发病机制的最新进展是通过三种遗传疾病来说明：冰岛和荷兰起源的遗传性淀粉样蛋白血管病和Gerstmann-Straussler-Scheinker病。
Amyloidosis and prionosis are disorders of protein conformation. The general mechanisms involved in amyloidogenesis are reviewed here. Recent progress in the molecular pathogenesis of cerebral amyloids is illustrated by three genetic disorders: hereditary amyloid angiopathies of Icelandic and Dutch origins and Gerstmann-Straussler-Scheinker disease.