Normal outcome of pregnancy in chronic myeloid leukemia treated with interferon-α in 1st trimester:: Report of 3 cases and review of the literature

Normal outcome of pregnancy in chronic myeloid leukemia treated with interferon-α in 1st trimester:: Report of 3 cases and review of the literature
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DOI:
10.1002/ajh.9876
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发表时间:
2002-02-01
影响因子:
12.8
通讯作者:
Al-Hassan, A
Al-Hassan, A
中科院分区:
医学1区
文献类型:
--
作者:
Mubarak, AAS;Kakil, IR;Al-Hassan, A

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三名慢性粒细胞白血病 (CML) 慢性期患者从妊娠第一个月开始在妊娠期间接受了干扰素-α治疗。没有报告孕产妇并发症。除了一名被发现患有短暂性轻度血小板减少症的婴儿外,这 3 名患者均产下外观正常的婴儿。随后对这些儿童进行了 30、12 和 4 个月的随访,结果均显示正常的生长发育。 (C) 2002 Wiley-Liss, Inc.
Three patients with Chronic Myeloid Leukemia (CML) in chronic phase received Interferon-alpha during pregnancy, starting from the 1(st) trimester. No maternal complications were reported. The 3 patients delivered normal looking babies apart from one baby who was found to have transient mild thrombocytopenia. Subsequently these children were followed for 30, 12, and 4 months and all had normal growth and development. (C) 2002 Wiley-Liss, Inc.