Early sexual abuse and lifetime psychopathology: a co-twin-control study
Early sexual abuse and lifetime psychopathology: a co-twin-control study
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DOI：
10.1017/s0033291799001373
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发表时间：
2000-01-01
影响因子：
6.9
通讯作者：
Martin, NG
中科院分区：
文献类型：
--
作者：
Dinwiddie, S;Heath, AC;Martin, NG
背景本研究旨在确定报告儿童期性虐待（CSA）的双胞胎中精神疾病的终生患病率，并将这些比率与非虐待双胞胎中的比率进行比较。贡献的家庭和个人的具体因素报告的性abuse.Method，终身精神病理学和物质使用的信息，获得了结构化的电话采访与5995澳大利亚双胞胎。将报告有儿童期性虐待（CSA）史的双胞胎与无此类病史的受试者进行终身精神病理学对比;此外，还对CSA不一致的同性双胞胎进行了比较。5.9%的女性和2.5%的男性报告了CSA病史。在整个样本中，那些报告CSA的人更有可能接受终身抑郁症，行为障碍，恐慌症和酗酒的诊断，并且更有可能报告自杀意念和自杀企图史。被虐待的女性，而不是男性，也更有可能报告社交恐惧症。当比较仅限于未受虐待的双胞胎时，未观察到精神病理学差异。然而，如果双胞胎都被虐待，则重度抑郁症，行为障碍和自杀意念的发生率高于单独报告CSA的应答者。模型拟合表明，共同的环境因素影响的风险，报告CSA的妇女，但不是在男性。CSA和精神病理学之间的关联至少部分是通过共同的家庭因素对受害风险和精神病理学风险的影响而产生的。
Background. This study was designed to determine lifetime prevalence of psychiatric disorders among twins who reported childhood sexual abuse (CSA), and to compare these rates with those among non-abused co-twins. The contribution of familial and individual-specific factors to reported sexual abuse was also examined.Method, Information about lifetime psychopathology and substance use was obtained by structured telephone interviews with 5995 Australian twins. Twins who reported a history of childhood sexual abuse (CSA) were contrasted on lifetime psychopathology with subjects without such a history; in addition, comparisons were made between same-sex twin pairs discordant for CSA.Results. A history of CSA was reported by 5.9 % of the women and 2.5 % of the men. In the sample as a whole, those reporting CSA were more likely to receive lifetime diagnoses of major depression, conduct disorder, panic disorder and alcoholism, and were more likely to report suicidal ideation and a history of suicide attempt. Abused women, but not men, were also more likely to report social phobia. When comparisons were restricted to non-abused co-twins, no differences in psy- chopathology were seen. However, rates of major depression, conduct disorder and suicidal ideation were higher if both co-twins were abused than if the respondent alone reported CSA. Model-fitting indicated that shared environmental factors influenced risk for reported CSA in women, but not in men.Conclusion. The association between CSA and psychopathology arises at least in part through the influence of shared familial factors on both risk of victimization and risk of psychopathology.