ADAPTATION OF THERMAL PAIN IN THE SKIN
ADAPTATION OF THERMAL PAIN IN THE SKIN
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DOI：
10.1152/jappl.1962.17.4.693
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发表时间：
1962-01-01
影响因子：
3.3
通讯作者：
HARDY, JD
中科院分区：
文献类型：
--
作者：
GREENE, LC;HARDY, JD
皮肤疼痛阈值测定在发黑的皮肤的额头和前臂的人类受试者超过16平方厘米的面积，通过记录皮肤温度在暴露于热辐射的时间长达50分钟。刺激的强度由受试者控制，使阈值疼痛保持在整个曝光。在受试者调整的初始阶段之后，辐射强度通常保持恒定，尽管用于疼痛阈值的皮肤温度从44.9 ℃降低到43.8 ℃。用低至22 mcal/cm ~ 2/sec的强度，在42.2 ℃的皮肤温度下，在29分钟内诱发阈痛。在这两组中，一旦疼痛被确定，它就不会消失。从这些观察结果推断，在30秒疼痛发作和刺激终止之间的时间段内，热痛不适应近阈值刺激。
Cutaneous pain thresholds were determined on blackened skin of foreheads and forearms of human subjects over areas of 16 cm2 by recording skin temperature during exposure to thermal radiation for periods up to 50 min. Intensity of stimulus was controlled by the subject so that threshold pain was maintained throughout the exposure. After the initial period of adjustment by the subject, radiation intensity was generally maintained constant although skin temperature for the pain threshold decreased from 44.9 C to 43.8 C. By using an intensity as low as 22 mcal/cm2 /sec, threshold pain was evoked in 29 min at a skin temperature of 42.2 C. In both groups, once pain had been established it did not disappear. It is inferred from these observations that thermal pain does not adapt for near-threshold stimulation in the period between onset of pain at 30 sec and termination of stimulation.