Impact of Exercise on Cerebrovascular Physiology and Risk of Stroke.

Impact of Exercise on Cerebrovascular Physiology and Risk of Stroke.
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运动对脑血管生理和中风风险的影响。

DOI:
10.1161/strokeaha.121.037343
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发表时间:
2022-07
期刊:
影响因子:
8.3
通讯作者:
--
中科院分区:
医学1区
文献类型:
--
作者:

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缺血性心脏病和中风分别是全球第一和第二大死亡原因。终身致力于锻炼可以降低这些不良事件的风险,并且还与几种心脏代谢改善相关,包括降低血压,胆固醇和炎症标志物,以及改善血糖控制。常规锻炼还可以降低患上增加心血管和/或脑血管疾病风险的合并症的风险。虽然终身致力于锻炼的益处已被充分证明,但锻炼与卒中风险之间存在复杂的相互作用,因此缺血性和/或出血性卒中的风险可能在锻炼期间或锻炼后立即急剧增加。在这篇文章中,我们讨论了不同类型的运动的生理反应,以及休息和劳力脑血管灌注的决定因素,并探讨心房颤动,运动和中风风险之间的复杂相互作用。最后,我们强调了在不同类型的运动中中风的风险增加,以及可能减轻这种风险的因素。
Ischemic heart disease and stroke are the #1 and #2 causes of death worldwide, respectively. A lifelong commitment to exercise reduces the risk of these adverse events and is also associated with several cardiometabolic improvements, including reductions in blood pressure, cholesterol and inflammatory markers, as well as improved glucose control. Routine exercise also reduces the risk of developing comorbidities that increase the risk of cardiovascular and/or cerebrovascular disease. While the benefits of a lifelong commitment to exercise are well documented, there is a complex interaction between exercise and stroke risk, such that the risk of ischemic and/or hemorrhagic stroke may increase acutely during or immediately following exercise. In this article, we discuss the physiologic responses to different types of exercise, as well as the determinants of resting and exertional cerebrovascular perfusion, and explore the complex interaction between atrial fibrillation, exercise and stroke risk. Finally, we highlight the increased risk of stroke during different types of exercise as well as factors that may alleviate this risk.
DOI: 10.1016/j.resp.2010.09.011
发表时间: 2011-01-31
影响因子: 2.3
作者:
Olin JT;Dimmen AC;Subudhi AW;Roach RC
通讯作者: Roach RC