DYSKINETIC CEREBRAL-PALSY .1. CLINICAL CATEGORIES, ASSOCIATED NEUROLOGICAL ABNORMALITIES AND INCIDENCES
DYSKINETIC CEREBRAL-PALSY .1. CLINICAL CATEGORIES, ASSOCIATED NEUROLOGICAL ABNORMALITIES AND INCIDENCES
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DOI：
10.1111/j.1651-2227.1982.tb09472.x
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发表时间：
1982-01-01
期刊：
影响因子：
--
通讯作者：
VOSS, H
中科院分区：
文献类型：
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作者：
KYLLERMAN, M;BAGER, B;VOSS, H
对出生于1959-1970年间的116例运动障碍脑性瘫痪患者进行分类，根据神经学标准分为35例(30%)和81例(70%)。在多动症患者中，80%有轻度运动障碍，而90%的肌张力障碍患者有中度或重度残疾。9%的肌张力亢进患者和44%的肌张力障碍患者存在附属痉挛体征。智商<90者占69%，肌张力障碍者占25%，<50者分别占11%和41%。在46%的多动症和81%的肌张力障碍患者中，还检测到两个或两个以上的神经系统异常(痉挛、智力低下、癫痫、构音障碍、构音障碍、听力障碍)。严重的多障碍复合体主要存在于肌张力障碍亚组。5-19岁死亡率为6%，仅限于最严重残疾的肌张力障碍病例。双胞胎比率为5%。总共有9%的人有出生体重。1500g，31%的人有.体重和年龄别发病率随着出生体重和胎龄的降低而迅速增加。多动型脑瘫的粗发病率为0.07%，肌张力障碍型脑瘫的粗发病率为0.17‰。
An unselected series of 116 dyskinetic cerebral palsy cases born during 1959-1970 was delineated and subgrouped according to neurological criteria into 35 hyperkinetic (30%) and 81 dystonic (70%) cases. Of the hyperkinetics, 80% had a mild motor disability, while 90% of the dystonics had moderate or severe disability. Subordinated spastic signs were found in 9% of the hyperkinetic and in 44% of the dystonic cases. IQ was > 90 in 69% of the hyperkinetics and 25% of the dystonics and < 50 in 11% and 41%, respectively. Two or more additional neurological abnormalities (spasticity, mental retardation, epilepsy, anarthria, dysarthria, hearing deficit) were detected in 46% hyperkinetic and 81% dystonic cases. A heavy multihandicap complex was present predominantly in the dystonic subgroup. The 5-19 yr mortality rate was 6% and was confined to the most severely handicapped dystonic cases. The twin rate was 5%. A total of 9% had birth weights .ltoreq. 1500 g, and 31% had .ltoreq. 2500 g. The weight- and age-specific incidences increased rapidly with decreasing birth weights and gestational ages. The crude incidence of hyperkinetic cerebral palsy was 0.07% and dystonic cerebral palsy 0.17 per thousand live births.