Solid-state fluoroscopic imager for high-resolution angiography: parallel-cascaded linear systems analysis.
Solid-state fluoroscopic imager for high-resolution angiography: parallel-cascaded linear systems analysis.
复制标题
用于高分辨率血管造影的固态荧光成像仪：并行级联线性系统分析。
DOI：
10.1118/1.1689014
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发表时间：
2004
期刊：
影响因子：
3.8
通讯作者：
Suryanarayanan,Sankararaman
中科院分区：
文献类型：
--
作者：
Vedantham,Srinivasan;Karellas,Andrew;Suryanarayanan,Sankararaman
基于级联线性系统的建模技术在过去已经被用于预测对图像质量具有直接影响的重要系统参数。这种模型在优化系统参数以提高图像质量方面也是有用的。在这项工作中，详细分析了固态荧光成像系统的高分辨率血管造影的使用这样一个模型。通过该模型分析的成像系统使用4个8×8 cm三面可对接内衬电荷耦合器件（CCD），专门设计用于高分辨率血管造影，并以无缝方式平铺，以实现16×16 cm的视野（FOV）。通过以类似的方式平铺更多的CCD可以实现更大的FOV。该系统采用CsI：Tl闪烁体通过直（非锥形）光纤耦合到CCD，并可能以78、156或234 μm像素间距模式工作。通过该模型分析了系统的预调制传递函数、噪声功率谱和量子探测效率。所执行的模拟结果表明，即使在1 μR/帧的低透视曝光率下，成像仪也可以在156 μm像素间距、30帧/秒的条件下工作，并采用450 μm厚的CsI：Tl闪烁体，DQE（0）超过0.6。此外，在2.5 μR/帧的标称透视曝光率下，即使在78 μm像素间距模式下，DQE也没有明显退化，这表明在临床实践中进行迄今无法实现的高分辨率血管造影是可行的。
Cascaded linear systems based modeling techniques have been used in the past to predict important system parameters that have a direct impact on image quality. Such models are also useful in optimizing system parameters to improve image quality. In this work, detailed analysis of a solid‐state fluoroscopic imaging system intended for high‐resolution angiography is presented with the use of such a model. The imaging system analyzed through this model uses four 8×8 cm three‐side buttable interlined charge‐coupled devices (CCDs) specifically designed for high‐resolution angiography and tiled in a seamless fashion to achieve a field of view (FOV) of 16×16 cm. Larger FOVs can be achieved by tiling more CCDs in a similar manner. The system employs a CsI:Tl scintillator coupled to the CCDs by straight (nontapering) fiberoptics and can potentially be operated in 78, 156, or 234 μm pixel pitch modes. The system parameters analyzed through this model include presampling modulation transfer function, noise power spectrum, and detective quantum efficiency (DQE). The results of the simulations performed indicate that DQE(0) in excess of 0.6 is achievable, with the imager operating at 156 μm pixel pitch, 30 frames/s, and employing a 450‐μm‐thick CsI:Tl scintillator, even at a low fluoroscopic exposure rate of 1 μR/frame. Further, at a nominal fluoroscopic exposure rate of 2.5 μR/frame there was no noticeable degradation of the DQE even at the 78 μm pixel pitch mode suggesting that it is feasible to perform high‐resolution angiography hitherto unattainable in clinical practice.