Radical external beam radiotherapy of urinary bladder carcinoma. An analysis of results in 500 patients.
Radical external beam radiotherapy of urinary bladder carcinoma. An analysis of results in 500 patients.
复制标题
膀胱癌的根治性外照射放射治疗。
DOI：
10.3109/02841869409083936
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发表时间：
1994
期刊：
影响因子：
3.1
通讯作者：
M. Weiss
中科院分区：
文献类型：
--
作者：
J. Skołyszewski;M. Reinfuss;M. Weiss
1970~1985年间，500例膀胱癌患者在Kraków肿瘤学中心接受了有治疗目的的外照射，T1组无癌生存100%(5/5)，T2组48.7%(19/39)，T3组32%(128/400)，T4组7.1%(4/56)。在我们的患者中，在单变量和多变量分析中，临床T分类是唯一具有统计学意义的治疗前预后参数。放疗前行经尿道膀胱肿瘤部分电切者及膀胱体积<200ml者对治疗的耐受性较差，局部(盆腔)淋巴结加量放疗可提高T3膀胱癌患者的生存率。
Between 1970 and 1985, 500 patients with urinary bladder carcinoma received external beam radiotherapy with curative intent at the Centre of Oncology in Kraków. The 5-year survival without evidence of cancer for T1 patients was 100% (5/5), for T2 48.7% (19/39), for T3 32% (128/400), and for T4 7.1% (4/56). In our patients the clinical T category was the only pretherapeutic prognostic parameter of statistical significance confirmed in uni- and multivariate analysis. The tolerance of therapy was poorer in patients who had partial transurethral resection of the bladder tumour performed prior to radiation therapy, and in those whose bladder volume was less than 200 ml. The additional irradiation of regional (pelvic) lymph nodes seemed to improve survival of patients with T3 bladder carcinoma.