Minimally invasive surgery improves short-term outcomes of nerve-sparing radical hysterectomy in patients with cervical cancer: a propensity-matched analysis with open abdominal surgery
Minimally invasive surgery improves short-term outcomes of nerve-sparing radical hysterectomy in patients with cervical cancer: a propensity-matched analysis with open abdominal surgery
复制标题
DOI：
10.3802/jgo.2019.30.e27
复制
发表时间：
2019-03-01
影响因子：
3.9
通讯作者：
Raspagliesi, Francesco
中科院分区：
文献类型：
--
作者：
Bogani, Giorgio;Rossetti, Diego;Raspagliesi, Francesco
目的：为了减少宫颈癌根治术患者的盆底功能障碍，已实施了保留神经的根治性子宫切除术。在这里，我们旨在调查采用腹腔镜手术是否会影响患者的预后。方法：将连续接受保留神经的腹腔镜下根治性子宫切除术的宫颈癌患者的数据与历史上接受开腹手术的患者进行1：1匹配。结果：纳入35例患者配对(70例患者：35例接受腹腔镜术，35例接受开腹神经保留的根治性子宫切除术)。人口统计学和基线肿瘤学特征在组之间是平衡的。接受腹腔镜手术的患者的手术时间与接受开腹手术的患者相似(249(+/-91.5)分钟比223[+/-65.0]分钟；p=0.066)。腹腔镜术与较少的出血量相关(30.5[+/-11.0]毫升比190[90.4]毫升；p
Objectives: Nerve-sparing radical hysterectomy has been implemented in order to reduce pelvic floor dysfunctions in women undergoing radical surgery for cervical cancer. Here, we aimed to investigate if the adoption of laparoscopic surgery impacts on patients' outcomes.Methods: Data of consecutive patients affected by cervical cancer who had laparoscopic nerve-sparing radical hysterectomy were matched 1:1 with an historical cohort of patients undergoing open procedure. A propensity-score matched algorithm was applied.Results: Thirty-five patients' pairs (70 patients: 35 undergoing laparoscopic vs. 35 undergoing open abdominal nerve-sparing radical hysterectomy) were included. Demographic and baseline oncologic characteristics were balanced between groups. Patients undergoing laparoscopic surgery had similar operative time than patients undergoing open abdominal procedures (249 (+/- 91.5] vs. 223 [+/- 65.0] minutes; p=0.066). Laparoscopic approach correlated with lower blood loss (30.5 [+/- 11.0] vs. 190 [90.4] mL; p