DNA Sequence Polymorphism Analysis Using DnaSP

DNA Sequence Polymorphism Analysis Using DnaSP
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DOI:
10.1007/978-1-59745-251-9_17
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发表时间:
2009-01-01
期刊:
BIOINFORMATICS FOR DNA SEQUENCE ANALYSIS
影响因子:
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通讯作者:
Rozas, Julio
Rozas, Julio
中科院分区:
其他
文献类型:
--
作者:
Rozas, Julio

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DNA序列多态性和SNP(单核苷酸多态性)的分析可以提供对种群和物种的进化力量的见解。现有的群体遗传学方法,特别是那些基于结合理论,已成为主要的框架来分析这样的DNA多态性数据。在这里,我解释了一些解释DNA多态性数据的基本分析方法,并描述了DnaSP软件的基本功能。DnaSP是一个多建议程序,允许使用图形用户友好的界面进行详尽的DNA多态性分析。
The analysis of DNA sequence polymorphisms and SNPs (single nucleotide polymorphisms) can provide insights into the evolutionary forces acting on populations and species. Available population-genetic methods, and particularly those based on the coalescent theory, have become the primary framework to analyze such DNA polymorphism data. Here, I explain some essential analytical methods for interpreting DNA polymorphism data and also describe the basic functionalities of the DnaSP software. DnaSP is a multi-propose program that allows conducting exhaustive DNA polymorphism analysis using a graphical user-friendly interface.