CONVERGENT DOMESTICATION OF CEREAL CROPS BY INDEPENDENT MUTATIONS AT CORRESPONDING GENETIC-LOCI
CONVERGENT DOMESTICATION OF CEREAL CROPS BY INDEPENDENT MUTATIONS AT CORRESPONDING GENETIC-LOCI
复制标题
DOI：
10.1126/science.269.5231.1714
复制
发表时间：
1995-09-22
期刊：
影响因子：
56.9
通讯作者：
IRVINE, JE
中科院分区：
文献类型：
--
作者：
PATERSON, AH;LIN, YR;IRVINE, JE
高粱、水稻和玉米的独立驯化包括对大种子的汇聚选择，减少成熟花序的脱节，以及对日长不敏感的开花。这些相似的表型在很大程度上是由在三个分类群中紧密对应的少量数量性状基因座(QTL)决定的。这些QTL的对应关系超越了6500万年的生殖隔离。这一发现支持数量遗传模型，这些模型引用的基因相对较少，避免了基于图谱的QTL克隆的困难，并推动了跨越大进化距离的复杂表型的比较图谱，例如将人类与啮齿动物和家养哺乳动物区分开来的那些。
Independent domestication of sorghum, rice, and maize involved convergent selection for large seeds, reduced disarticulation of the mature inflorescence, and daylength-insensitive flowering. These similar phenotypes are largely determined by a small number of quantitative trait loci (QTLs) that correspond closely in the three taxa. The correspondence of these QTLs transcends 65 million years of reproductive isolation. This finding supports models of quantitative inheritance that invoke relatively few genes, obviates difficulties in map-based cloning of QTLs, and impels the comparative mapping of complex phenotypes across large evolutionary distances, such as those that separate humans from rodents and domesticated mammals.