Sympathetic-Parasympathetic Interaction and Externalizing Problems in Children with Autism Spectrum Disorder
Sympathetic-Parasympathetic Interaction and Externalizing Problems in Children with Autism Spectrum Disorder
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DOI：
10.1002/aur.2187
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发表时间：
2019-08-09
期刊：
影响因子：
4.7
通讯作者：
Kaeppler, Alexander K.
中科院分区：
文献类型：
--
作者：
Fenning, Rachel M.;Erath, Stephen A.;Kaeppler, Alexander K.
自闭症谱系障碍（ASD）儿童表现出情绪调节和反应的显着困难，这可能与潜在的心理生理学。本研究探讨了自闭症儿童自主神经系统活动与外化行为问题个体差异之间的关系。采用多系统方法来考虑交感神经（皮肤电反应-EDA-R）和副交感神经反应（呼吸性窦性心律失常反应-RSA-R）标记物与行为挑战之间的相互作用。52名6-10岁ASD儿童提供了完整的心理生理数据。EDA-R和RSA-R（RSA戒断）的措施，获得在实验室的挑战任务和父母报告的儿童外化行为问题，使用标准化的问卷调查和结构化的临床访谈。一个equifinality模型的支持，有两个不同的心理生理途径与提高外化行为问题。更大的RSA-R与更多的外部化问题的背景下，更高水平的EDA-R，和较低的EDA-R与增加外部化问题在较低水平的RSA-R。研究结果强调了考虑心理生理学在ASD儿童共病外化问题中的作用的重要性。定制的共同监管支持的潜在影响进行了讨论。自闭症研究2019，00：1-15。(c)2019年国际自闭症研究学会，Wiley Periodicals，Inc。摘要自闭症谱系障碍（ASD）儿童表现出较高的挑战行为率。这项研究确定了特定的心理生理特征（低交感神经-低副交感神经反应，高交感神经-高副交感神经反应），可能会使这些儿童面临更大的行为问题风险。研究结果对更好地理解ASD儿童的行为挑战以及定制支持以解决潜在的心理生理学问题具有重要意义。
Children with autism spectrum disorder (ASD) exhibit significant difficulties with emotion regulation and reactivity, which may be linked to underlying psychophysiology. The present study examined associations between autonomic nervous system activity and individual differences in externalizing behavior problems in children with ASD. A multisystem approach was adopted to consider the interplay between markers of sympathetic (electrodermal reactivity-EDA-R) and parasympathetic reactivity (respiratory sinus arrhythmia reactivity-RSA-R) in relation to behavioral challenges. Fifty-two children with ASD ages 6-10 years contributed complete psychophysiological data. Measures of EDA-R and RSA-R (RSA withdrawal) were obtained in response to a laboratory challenge task and parents reported on child externalizing behavior problems using a standardized questionnaire and a structured clinical interview. An equifinality model was supported, with two distinct psychophysiological pathways linked to heightened externalizing behavior problems. Greater RSA-R was associated with more externalizing problems in the context of higher levels of EDA-R, and lower EDA-R was associated with increased externalizing problems at lower levels of RSA-R. Findings underscore the importance of considering the role of psychophysiology in the unfolding of comorbid externalizing problems in children with ASD. Potential implications for tailoring coregulatory supports are discussed. Autism Res 2019, 00: 1-15. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary Children with autism spectrum disorder (ASD) exhibit elevated rates of challenging behavior. This study identified specific psychophysiological profiles (low sympathetic-low parasympathetic reactivity, and high sympathetic-high parasympathetic reactivity) that may place these children at greater risk for behavior problems. Findings have implications for better understanding behavioral challenges in children with ASD, and for tailoring supports to address underlying psychophysiology.