Performance evaluation of adaptive meshing algorithms for fluorescence diffuse optical tomography using experimental data.

Performance evaluation of adaptive meshing algorithms for fluorescence diffuse optical tomography using experimental data.
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DOI:
10.1364/ol.35.003727
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发表时间:
2010-11
期刊:
影响因子:
3.6
通讯作者:
Lu Zhou;B. Yazıcı;A. Ale;V. Ntziachristos
Lu Zhou;B. Yazıcı;A. Ale;V. Ntziachristos
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Lu Zhou;B. Yazıcı;A. Ale;V. Ntziachristos

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荧光漫射光学层析成像(FDOT)是一个计算要求很高的成像问题。FDOT正反问题的离散化需要在图像重建的精度和计算效率之间进行权衡。为了解决这个问题,我们分析了离散化对FDOT成像精度的影响,并在一系列研究中提出了新的FDOT自适应网格算法。在这篇文章中,我们将这些新的自适应网格算法应用于FDOT成像,并使用来自幻像实验的真实数据来证明我们的算法在FDOT图像重建中的实际优势。
Fluorescence diffuse optical tomography (FDOT) is a computationally demanding imaging problem. The discretizations of FDOT forward and inverse problems pose a trade-off between the accuracy and the computational efficiency of the image reconstruction. To address this trade-off, we analyzed the effect of discretization on the accuracy of FDOT imaging and proposed novel adaptive meshing algorithms for FDOT in a series of studies. In this Letter, we apply these new adaptive meshing algorithms to FDOT imaging using real data from a phantom experiment to demonstrate the practical advantages of our algorithms in FDOT image reconstruction.