CHARACTERIZATION OF A CALICI-LIKE VIRUS (NEWBURY AGENT) FOUND IN ASSOCIATION WITH ASTROVIRUS IN BOVINE DIARRHEA
CHARACTERIZATION OF A CALICI-LIKE VIRUS (NEWBURY AGENT) FOUND IN ASSOCIATION WITH ASTROVIRUS IN BOVINE DIARRHEA
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DOI：
10.1128/iai.43.1.133-138.1984
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发表时间：
1984-01-01
影响因子：
3.1
通讯作者：
BROWN, JF
中科院分区：
文献类型：
--
作者：
BRIDGER, JC;HALL, GA;BROWN, JF
一种牛钙样病毒和星状病毒，存在于腹泻爆发的同一粪便样本中，通过小牛通道相互分离。钙样病毒（Newbury代理SRV-1）引起17 ~ 60日龄肉牛厌食、腹泻和木糖吸收不良；牛星状病毒在相似的小牛中无致病性。在小牛中进行的双向交叉保护实验表明，钙样病毒在抗原性上与先前描述的分离物（纽伯里病毒SRV-2）不同；对同种病毒免疫的犊牛在异源病毒攻毒后出现临床发病和排泄病毒。
A bovine calici-like virus and astrovirus, present in the same fecal sample from an outbreak of diarrhea, were separated from each other by calf passage. The calici-like virus (Newbury agent SRV-1) caused anorexia, diarrhea and xylose malabsorption in gnotobiotic calves aged 17-60 days; the bovine astrovirus was nonpathogenic in similar calves. The calici-like virus was shown to be antigenically distinct from a previously described isolate (Newbury agent SRV-2) by 2 way cross-protection experiments in calves; calves immune to homologous challenged became clinically ill and excreted virus when challenged with the heterologous virus.