Serous surface papillary carcinoma. A clinicopathologic study of 10 cases and comparison with stage III-IV ovarian serous carcinoma.
Serous surface papillary carcinoma. A clinicopathologic study of 10 cases and comparison with stage III-IV ovarian serous carcinoma.
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DOI：
10.1097/00000478-198811000-00003
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发表时间：
1988-11
期刊：
影响因子：
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通讯作者：
Stacey E. Mills;Willie A. Andersen;Robert E. Fechner;Mark B. Austin
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文献类型：
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作者：
Stacey E. Mills;Willie A. Andersen;Robert E. Fechner;Mark B. Austin
我们比较了10例浆液性表面乳头状癌（SSPC）和16例浆液性卵巢乳头状癌（SOPC）的对照组。根据定义，SSPC的卵巢大小和形状正常。然而，在6例病例中，至少有一个卵巢有局灶性表面不规则。显微镜下，SSPC和SOPC仅在卵巢受累的性质上不同。SSPC局限于卵巢表面或显示局灶性微小浸润。4例SSPC患者同时存在非腹膜浆液性癌，3例为浅表性子宫内膜腺癌，1例为输卵管粘膜内腺癌。SOPC组中无相关癌。根据中位无病期（SSPC：3个月，SOPC：9个月）、中位生存期（SSPC：12个月，SOPC：24个月）和预测5年生存期（SSPC：52个月时全部死亡，SOPC：22.7%）衡量，SSPC的预后明显差于SOPC。SSPC是浆液性癌的一种临床病理学特征性变异。由于其更具侵略性的临床过程，它应该区别于传统的SOPC与腹膜植入物。
We compared 10 patients with serous surface papillary carcinoma (SSPC) to a control group of 16 patients with serous ovarian papillary carcinoma (SOPC). By definition, the ovaries were of normal size and shape in SSPC. In six cases, however, at least one ovary had focal surface irregularities. Microscopically, SSPC and SOPC differed only in the nature of their ovarian involvement. SSPC was confined to the ovarian surface or showed focal minimal invasion. Four patients with SSPC had coexistent, nonperitoneal serous-type carcinomas; three had superficial endometrial adenocarcinomas; and one had intramucosal adenocarcinoma of the fallopian tube. There were no associated carcinomas in the SOPC group. SSPC had a significantly worse prognosis than SOPC, as measured by median disease-free interval (SSPC: 3 months, SOPC: 9 months), median survival (SSPC: 12 months, SOPC: 24 months), and predicted 5-year survival (SSPC: all dead at 52 months, SOPC: 22.7%). SSPC is a clinicopathologically distinctive variant of serous carcinoma. Because of its more aggressive clinical course, it should be distinguished from conventional SOPC with peritoneal implants.