On the evolution of Boolean networks for computation: a guide RNA mechanism
On the evolution of Boolean networks for computation: a guide RNA mechanism
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计算布尔网络的演化：引导RNA机制
DOI：
10.1080/17445760.2015.1057590
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
L. Bull
中科院分区：
文献类型：
--
作者：
L. Bull
在计算智能领域，有越来越多的工作探索生物细胞遗传调控网络启发下的表征的使用。本文使用最近提出的这类网络的一个抽象的、可调的模型来研究如何通过动态重新布线连接的能力来通过模拟进化来影响它们的设计。由其他分子对转录的RNA进行上下文编辑，从而使最终产物的形式与相应DNA序列中指定的形式不同的情况随处可见。这里表明，可以在各种情况下选择向导RNA启发的编辑机制。
There is a growing body of work within computational intelligence which explores the use of representations inspired by the genetic regulatory networks of biological cells. This paper uses a recently presented abstract, tunable model of such networks to investigate how their design through simulated evolution is affected through the ability to dynamically rewire connectivity. The contextual editing of transcribed RNA by other molecules such that the form of the final product differs from that specified in the corresponding DNA sequence is ubiquitous. It is here shown that a guide RNA-inspired editing mechanism can be selected for under various scenarios.
影响因子：
2
作者：
KAUFFMAN, SA;JOHNSEN, S
通讯作者：
JOHNSEN, S