Homelessness Independently Predicts Injection Drug Use Initiation Among Street-Involved Youth in a Canadian Setting
Homelessness Independently Predicts Injection Drug Use Initiation Among Street-Involved Youth in a Canadian Setting
复制标题
DOI：
10.1016/j.jadohealth.2012.07.011
复制
发表时间：
2013-04-01
影响因子：
7.6
通讯作者：
Wood, Evan
中科院分区：
文献类型：
--
作者：
Feng, Cindy;DeBeck, Kora;Wood, Evan
目的：这项纵向研究探讨了在水晶甲基苯丙胺使用高流行率的情况下，一群街头青少年中无家可归与开始注射吸毒之间的关联。方法：我们从高危青少年研究中获取数据，该研究是一个 14-26 岁街头青少年的前瞻性队列，于 2005 年 9 月至 2011 年 11 月期间招募。我们使用 Cox 比例风险回归来确定与开始注射时间独立相关的因素。在 422 名基线时从未注射过的街头青少年中，我们在随访期间观察到 77 起注射起始事件。在调整了冰毒使用和其他潜在混杂因素后，在多变量 Cox 回归中，无家可归与注射开始独立相关（相对风险，1.80 [95% 置信区间，1.13-2.87]）。结论：这些发现强调，无家可归是街头青少年开始注射的一个关键风险因素。对街头青少年的支持性住房干预措施可能有助于防止这一高危人群开始注射吸毒。 (C) 2013 年青少年健康与医学协会。版权所有。
Purpose: This longitudinal study examines the association between homelessness and injection drug use initiation among a cohort of street-involved youth in a setting of high-prevalence crystal methamphetamine use.Methods: We derived data from the At-Risk Youth Study, a prospective cohort of street-involved youth aged 14-26 years, recruited between September 2005 and November 2011. We used Cox proportional hazards regression to identify factors independently associated with time to injection initiation.Results: Among 422 street-youth who had never injected at baseline, we observed 77 injection initiation events during follow-up. Homelessness was independently associated with injection initiation in multivariate Cox regression (relative hazard, 1.80 [95% confidence interval, 1.13-2.87]) after adjusting for crystal methamphetamine use and other potential confounders.Conclusions: These findings highlight that homelessness is a key risk factor for injection initiation among street-involved youth. Supportive housing interventions for street youth may help prevent injection drug use initiation within this high-risk population. (C) 2013 Society for Adolescent Health and Medicine. All rights reserved.