[Clinical study on prognostic factors in thyroid carcinoma].
[Clinical study on prognostic factors in thyroid carcinoma].
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甲状腺癌预后因素的临床研究[J].
DOI：
10.3950/jibiinkoka.104.157
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发表时间：
2001
期刊：
影响因子：
--
通讯作者：
M. Nishikawa
中科院分区：
文献类型：
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作者：
T. Tachikawa;H. Kumazawa;R. Kyomoto;H. Yukawa;T. Yamashita;M. Nishikawa
1984年至1998年，我们医院治疗了227名甲状腺癌患者，其中男性45名，女性182名。其中，177名患有乳头状癌，50名滤泡状癌。乳头状癌的切除范围取决于肿瘤大小，但滤泡状癌则不然，70%的癌症患者接受了半甲状腺切除术。 93.2%的乳头状癌患者进行了颈部淋巴结切除，其中D1颈清扫术占45.7%，D2或D3颈清扫术占47.5%。相比之下，70%接受淋巴结切除的滤泡癌患者进行了D1清扫。局部复发22例，远处转移6例。死亡人数为 17 人，其中 12 名乳头状癌患者和 5 名滤泡状癌患者死于原发病。几乎所有死亡均为晚期患者，pT3 3例，pT4 10例，N1a 3例，N1b 8例。乳头状癌的预后因素是囊外扩散、年龄和远处转移，而滤泡状癌的唯一因素是远处转移。乳头状癌患者的 5 年生存率为 93.0%，10 年生存率为 88.8%，而滤泡癌患者的 5 年生存率为 93.5%，10 年生存率为 93.5%。
We treated 227 patients, 45 men and 182 women, with thyroid carcinoma at our hospital from 1984 to 1998. Of these, 177 had papillary carcinoma and 50 follicular carcinoma. The extent of resection was based on tumor size in papillary carcinoma but not follicular carcinoma, and 70% of carcinoma patients underwent hemithyroidectomy. Neck lymph nodes were resected in 93.2% of papillary carcinoma patients, with D1 neck dissection in 45.7% and D2 or D3 neck dissection in 47.5%. In contrast, 70% of follicular carcinoma patients with lymph node resection had D1 dissection. Locoregional recurrence was noted in 22 patients and distant metastasis in 6 cases. Nonsurvivors numbered 17, 12 papillary and 5 follicular carcinoma patients, died of their primary disease. Almost all deaths were in patients with advanced disease, pT3 in 3, pT4 in 10, N1a in 3 and N1b in 8. The prognostic factors for papillary carcinoma were extracapsular spread, age, and distant metastasis, while the only factor for follicular carcinoma was distant metastasis. The 5-year survival for patients with papillary carcinoma was 93.0% and 10-year survival 88.8%, compared to 5-year survival for 93.5% of follicular carcinoma patients and 10-year survival for 93.5%.