Genome scanning
Genome scanning
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基因组扫描
DOI：
10.1002/9783527678679.dg05081
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发表时间：
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期刊：
影响因子：
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通讯作者：
L. K. Ernst
中科院分区：
文献类型：
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作者：
N. Zinovieva;A. Dotsev;A. Sermyagin;K. Wimmers;H. Reyer;J. S. Ö. Lkner;T. Deniskova;G. Brem;L. K. Ernst
随着牛基因组全序列的公布，基于全基因组SNP筛选的结果，追踪品种起源的历史和评估现代品种之间的遗传关系成为可能。在全基因组水平上对欧洲、北美、亚洲和非洲的商品牛品种和一些地方牛品种进行了大量的研究，但对俄罗斯地方牛品种的遗传差异、亲缘关系和群体遗传结构知之甚少。利用美国加州圣地亚哥Illumina牛SNP50 BeadChips产生的全基因组单核苷酸多态(SNPs)，研究了5个地方培育的俄罗斯黄牛品种的遗传多样性和群体结构。总共分析了来自5个品种的116个样本(精子或组织)，其中包括Bestuzhev(BEST，n=27)、Kholmogor(KHLM，n=25)、Ko-stromsky(KSTR，n=20)、Red Gorbatov(RGBT，n=23)和Yarola vl品种(n=21)。以29头荷斯坦牛(HLST，n=29)为对照。在Plink v1.07中进行遗传标记的质量筛选。使用软件plink 1.07，HP-Rare 1.1，Structure，Ver进行数据处理。2.3.4，佛蒙特州菲利普3.695，Figtree
With the publication of the complete sequence of a cattle genome, it became possible to trace the history of breed origins and to evaluate genetic relationships between modern breeds, based on the results of genome-wide SNP screening. Whilst numerous studies have been undertaken to characterize the commercial breeds and some local cattle breeds of Europe, North America, Asia and Africa at whole-genome level, little is known about genetic differences, relationships and population genetic structure of the Russian native cattle breeds. The aim of our work was to study the ge-netic diversity and population structure of five locally-developed Russian cattle breeds, based on genome-wide single nucleotide polymorphisms (SNPs) generated using Illumina Bovine SNP50 BeadChips (Illumina, San Diego, CA, USA). In total, 116 samples (sperm or tissue) collected from five breeds were analyzed, including Bestuzhev (BEST, n = 27), Kholmogor (KHLM, n = 25), Ko-stromsky (KSTR, n = 20), Red Gorbatov (RGBT, n = 23) and Yaroslavl breeds (YRSL, n = 21). Samples of Holstein cattle (HLST, n = 29) were used for comparison. Quality filtering of genetic markers was performed in PLINK v 1.07. Data processing was performed using software PLINK 1.07, HP-Rare 1.1, STRUCTURE, ver. 2.3.4, Phylip, ver. 3.695, FigTree
DOI：
10.1111/j.1471-8286.2004.00845.x
发表时间：
2005-03-01
期刊：
MOLECULAR ECOLOGY NOTES
影响因子：
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作者：
Kalinowski, ST
通讯作者：
Kalinowski, ST