Lipase of Malassezia furfur: some properties and their relationship to cell growth.
Lipase of Malassezia furfur: some properties and their relationship to cell growth.
复制标题
糠秕马拉色菌的脂肪酶：一些特性及其与细胞生长的关系。
DOI：
10.1080/02681219380000081
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
Hideoki Ogawa
中科院分区：
文献类型：
--
作者：
Y. Ran;T. Yoshiike;Hideoki Ogawa
脂肪酶活性的马拉色菌糠秕，检测与α-萘棕榈酸酯作为底物，似乎是与有机体的不溶性部分。M的轮廓。糠醛脂肪酶与Candida cylindracea脂肪酶相似。脂肪酶的最适pH为酸性，pH 5.0，这是非常相似的皮肤表面的pH值。酶的活性被强烈激活的脂肪酶激活剂，牛磺胆酸钠（STC）。此外，STC的培养基中激活细胞生长的剂量依赖性的方式和诱导菌丝的生产。这些结果表明M.糠醛脂肪酶在细胞生长中起重要作用。
Lipase activity of Malassezia furfur, detected with alpha-naphthyl palmitate as a substrate, appeared to be associated with the insoluble fraction of the organism. Profiles of M. furfur lipase were similar to those of Candida cylindracea lipase. The pH optimum of the lipase was acidic, pH 5.0, which is very similar to skin surface pH. The enzyme activity was strongly activated by a lipase activator, sodium taurocholate (STC). Addition of STC to the culture medium activated cell growth in a dose-dependent manner and induced hyphae production. These results suggest that M. furfur lipase plays an important role in cell growth.