Formal education as an effect modifier of the relationship between Mini-Mental State Examination score and IADLs disability in the older population
Formal education as an effect modifier of the relationship between Mini-Mental State Examination score and IADLs disability in the older population
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DOI：
10.1007/bf03340146
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发表时间：
1997-06-01
影响因子：
4
通讯作者：
Bavazzano, A
中科院分区：
文献类型：
--
作者：
Quesada, JJ;Ferrucci, L;Bavazzano, A
这项回顾性病例系列研究的目的是探讨工具性日常生活活动（IADL）残疾与简易精神状态检查（MMSE）测量的认知障碍之间的关系，以及这种关系如何受到不同水平的正规教育的影响。该研究的背景是普拉托（意大利）第4地方卫生单位（USL）的认知障碍中心。IADL的独立性与MMSE评分密切相关。MMSE评分小于24分可预测至少一项IADL的残疾，敏感性为0.82，特异性为0.73。然而，当仅考虑具有非常低的正规教育水平的人时，预测IADL残疾的最佳阈值为17（敏感性0.76，特异性0.75）。因此，学业成绩是认知状态（如MMSE所测量）与IADL残疾之间关系的影响因素。受教育程度低和MMSE表现差的受试者通常独立于对认知功能有要求的活动，如IADL。这些结果表明，较低的MMSE截止评分时，应考虑这些人的认知功能障碍筛查。(C)1997年，编辑柯蒂斯。
The objective of this retrospective, case-series study was to examine the relationship between disability in Instrumental Activities of Daily Living (IADLs) and cognitive impairment measured by the Mini-Mental State Examination (MMSE), and how this relationship was influenced by different levels of formal education. The setting of the study was the Cognitive Disorders Center of the Local Sanitary Unit (USL) No. 4 in Prato (Italy). Independence in IADL was strongly related to MMSE scores. A score of less than 24 at the MMSE was predictive of disability in at least one IADL with 0.82 sensitivity and 0.73 specificity. However, when only people with a very low level of formal education were considered, the best threshold predicting IADL disability was 17 (sensitivity 0.76, specificity 0.75). Thus, scholastic achievement is an effect modifier of the relationship between cognitive status, as measured by the MMSE, and IADL disability. Subjects with low education level and poor performance at the MMSE are often independent in activities making demand on cognitive function, such as IADLs. These results suggest that a lower MMSE cut-off score should be considered when screening for cognitive impairment in these persons. (C) 1997, Editrice Kurtis.