Phonological Working Memory for Words and Nonwords in Cerebral Cortex.
Phonological Working Memory for Words and Nonwords in Cerebral Cortex.
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大脑皮层中单词和非单词的语音工作记忆。
DOI：
10.1044/2017_jslhr-l-15-0446
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
Kovelman,Ioulia
中科院分区：
文献类型：
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作者：
Perrachione,TylerK;Ghosh,SatrajitS;Ostrovskaya,Irina;Gabrieli,JohnDE;Kovelman,Ioulia
本研究的主要目的是通过类似于临床上敏感的非单词重复评估的行为任务来确定语音工作记忆（语音的短期维持）的脑基础。本研究的第二个目的是确定如何在大脑激活的个体差异与参与者的nonword repeatability.MethodWe使用功能磁共振成像测量神经生理反应的非字歧视任务来自标准临床评估的语音工作记忆。健康成人对照组（N= 16）歧视对真实的字或nonwords不同的语音工作记忆负荷，我们操纵的参数变化的目标（非）字的音节数。参与者的认知和语音能力也进行了测量，使用标准化assessment.ResultsNeuropathical反应在双边上级颞回，额下回，和补充运动区增加更大的语音工作记忆负荷。激活在左上级颞回在非词歧视与参与者的标准临床nonword repetition tests.ConclusionThese结果表明，语音工作记忆的功能相关的皮质结构，规范的语音感知和生产的基础。
PurposeThe primary purpose of this study was to identify the brain bases of phonological working memory (the short-term maintenance of speech sounds) using behavioral tasks analogous to clinically sensitive assessments of nonword repetition. The secondary purpose of the study was to identify how individual differences in brain activation were related to participants' nonword repetition abilities.MethodWe used functional magnetic resonance imaging to measure neurophysiological response during a nonword discrimination task derived from standard clinical assessments of phonological working memory. Healthy adult control participants (N= 16) discriminated pairs of real words or nonwords under varying phonological working memory load, which we manipulated by parametrically varying the number of syllables in target (non)words. Participants' cognitive and phonological abilities were also measured using standardized assessments.ResultsNeurophysiological responses in bilateral superior temporal gyrus, inferior frontal gyrus, and supplementary motor area increased with greater phonological working memory load. Activation in left superior temporal gyrus during nonword discrimination correlated with participants' performance on standard clinical nonword repetition tests.ConclusionThese results suggest that phonological working memory is related to the function of cortical structures that canonically underlie speech perception and production.