High plasma HIV load in the CRF01-AE outbreak among injecting drug users in Finland
High plasma HIV load in the CRF01-AE outbreak among injecting drug users in Finland
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DOI：
10.1080/00365540410021054
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发表时间：
2005-04-01
影响因子：
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通讯作者：
Ristola, MA
中科院分区：
文献类型：
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作者：
Kivelä, PS;Krol, A;Ristola, MA
1998年在芬兰注射毒品使用者中发现了由重组AE亚型（CRF 01-AE）引起的HIV-1爆发。将这些IDU与来自阿姆斯特丹队列研究（ACS）的感染B亚型的IDU进行比较，以检测感染不同亚型的2个西方IDU队列之间可能存在的差异。比较了93例CRF 01-AE IDUs和63例B亚型IDUs的进展标志物（病毒载量和CD 4+淋巴细胞计数）。只有血清转换间隔期的人
An explosive outbreak of HIV-1 caused by the recombinant subtype AE (CRF01-AE) was detected in 1998 among Finnish injecting drug users (IDUs). These IDUs were compared with IDUs from the Amsterdam Cohort Study (ACS) infected with subtype B, to detect possible differences between 2 western IDU cohorts infected with different subtypes. Markers for progression ( viral load and CD4+ lymphocyte count) were compared between 93 IDUs with CRF01-AE and 63 IDUs with subtype B. Only persons with a seroconversion interval