The first four cases of successful NeoChord procedure in mainland China.
The first four cases of successful NeoChord procedure in mainland China.
复制标题
中国大陆首例NeoChord手术成功四例。
DOI：
10.5847/wjem.j.1920-8642.2019.03.001
复制
发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Wang JA
中科院分区：
文献类型：
--
作者：
Wang LH;Pu ZX;Kong MJ;Jiang JB;Ren KD;Gao F;Lin XP;Yu L;He W;Yan M;Liu XB;Wang JA
背景
经心尖非体外循环NeoChord手术是治疗退行性二尖瓣返流(MR)的一种新的微创手术方式。在这里，我们报告了内地首4例二尖瓣脱垂患者行NeoChord手术，中国。
方法
2 0 19年4月9日和10日，4例因中后扇贝脱垂(P2)导致严重MR的患者，年龄分别为86岁、84岁、80岁和60岁，接受了经根尖非体外循环人工脊索植入术。手术在二维和三维经食道超声心动图(TEE)引导下，在全麻下经左胸小切口完成。
结果
经NeoChord手术二尖瓣成形术成功，1例植入3根人工脊索，随后植入3根、2根和3根人工脊索。术中TEE和出院前经胸超声心动图(TTE)显示这4例患者的MR只是轻到中度，没有发现术后并发症。术后1个月随访至出院前TTE检查结果无明显变化。
结论
4例中国人成功的NeoChord手术表明，在中国人群中应用NeoChord系统进行瓣膜修复是可行的。
BACKGROUND
Transapical off-pump NeoChord procedure is a novel minimally invasive surgical repair of degenerative mitral regurgitation (MR). Here, we report the first four cases of NeoChord procedure in patients with mitral valve prolapse in mainland China.
METHODS
Four patients, aged 86, 84, 80 and 60 years, with severe MR due to posterior middle scallop prolapse (P2), underwent transapical off-pump artificial chordae implantation on April 9 and 10, 2019. The procedure was performed by left mini-thoracotomy under general anaesthesia and guided by 2D and 3D dimensional transoesophageal echocardiography (TEE).
RESULTS
Mitral valve repair via NeoChord procedure was successfully performed with implantation of 3 artificial chordae in the first patient and 3, 2, and 3 artificial chordae in the following patients, respectively. Intraoperative TEE and pre-discharge transthoracic echocardiography (TTE) showed only mild to moderate MR of these four patients and no postoperative complications were noted. There were no changes of TTE finding between one-month follow-up and pre-discharge.
CONCLUSION
The successful NeoChord procedures in four Chinese indicate that the valve repair using the NeoChord system for Chinese population is feasible.