Intranasal immunization with phosphorylcholine suppresses allergic rhinitis in mice

Intranasal immunization with phosphorylcholine suppresses allergic rhinitis in mice
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DOI：
10.1002/lary.27030
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发表时间：
2018-07
期刊：
The Laryngoscope
影响因子：
--
通讯作者：
Keiichi Miyashita;J. Ohori;H. Nagano;S. Fukuyama;Y. Kurono
Keiichi Miyashita;J. Ohori;H. Nagano;S. Fukuyama;Y. Kurono
中科院分区：
其他
文献类型：
--
作者：
Keiichi Miyashita;J. Ohori;H. Nagano;S. Fukuyama;Y. Kurono

文献摘要

相似文献

众所周知，磷胆碱(PC)鼻腔免疫可减少免疫球蛋白(Ig)E的产生。然而，其对变应性鼻炎(AR)发生的影响尚不清楚。本研究旨在评价PC-锁孔帽状血蓝蛋白(PC-KLH)对AR小鼠模型的作用及其对AR发生的影响。
Intranasal immunization with phosphorylcholine (PC) is known to reduce immunoglobulin (Ig)E production. However, its effects on the occurrence of allergic rhinitis (AR) are unknown. This study was performed to evaluate the effects of PC‐keyhole limpet hemocyanin (PC‐KLH) and to examine the effects on the occurrence of AR in a murine model of AR.