The ecoresponsive genome of Daphnia pulex.
The ecoresponsive genome of Daphnia pulex.
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DOI：
10.1126/science.1197761
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发表时间：
2011-02-04
期刊：
影响因子：
--
通讯作者：
Boore JL
中科院分区：
文献类型：
--
作者：
Colbourne JK;Pfrender ME;Gilbert D;Thomas WK;Tucker A;Oakley TH;Tokishita S;Aerts A;Arnold GJ;Basu MK;Bauer DJ;Cáceres CE;Carmel L;Casola C;Choi JH;Detter JC;Dong Q;Dusheyko S;Eads BD;Fröhlich T;Geiler-Samerotte KA;Gerlach D;Hatcher P;Jogdeo S;Krijgsveld J;Kriventseva EV;Kültz D;Laforsch C;Lindquist E;Lopez J;Manak JR;Muller J;Pangilinan J;Patwardhan RP;Pitluck S;Pritham EJ;Rechtsteiner A;Rho M;Rogozin IB;Sakarya O;Salamov A;Schaack S;Shapiro H;Shiga Y;Skalitzky C;Smith Z;Souvorov A;Sung W;Tang Z;Tsuchiya D;Tu H;Vos H;Wang M;Wolf YI;Yamagata H;Yamada T;Ye Y;Shaw JR;Andrews J;Crease TJ;Tang H;Lucas SM;Robertson HM;Bork P;Koonin EV;Zdobnov EM;Grigoriev IV;Lynch M;Boore JL
我们描述了微甲壳类水蚤（Daphnia pulex）的基因组草图，它只有200 Mb，包含至少30,907个基因。高基因计数是基因复制率升高导致串联基因簇的结果。超过1/3的水蚤基因在任何其他可用的蛋白质组中都没有可检测到的同源物，并且扩增最多的基因家族是水蚤谱系特有的。基因家族在代谢途径中相互作用的共同扩展表明，重复基因的维持不是随机的，对不同环境条件下基因表达的分析表明，许多类似物在复制后不久就获得了不同的表达模式。水蚤特有的基因是对生态挑战最敏感的基因，包括许多在测序区域内没有注释的额外基因座。
We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200 Mb and contains at least 30,907 genes. The high gene count is a consequence of an elevated rate of gene duplication resulting in tandem gene clusters. More than 1/3 of Daphnia’s genes have no detectable homologs in any other available proteome, and the most amplified gene families are specific to the Daphnia lineage. The co-expansion of gene families interacting within metabolic pathways suggests that the maintenance of duplicated genes is not random, and the analysis of gene expression under different environmental conditions reveals that numerous paralogs acquire divergent expression patterns soon after duplication. Daphnia-specific genes – including many additional loci within sequenced regions that are otherwise devoid of annotations – are the most responsive genes to ecological challenges.
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影响因子：
4.8
作者：
Kimura, S;Tokishita, S;Yamagata, H
通讯作者：
Yamagata, H
影响因子：
10.7
作者：
Katju, V;Lynch, M
通讯作者：
Lynch, M
影响因子：
12.3
作者：
Kondrashov FA;Rogozin IB;Wolf YI;Koonin EV
通讯作者：
Koonin EV
DOI：
10.1007/s003590050293
发表时间：
1998-12-01
期刊：
JOURNAL OF COMPARATIVE PHYSIOLOGY A-SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY
影响因子：
--
作者：
Storz, UC;Paul, RJ
通讯作者：
Paul, RJ
DOI：
10.1098/rspb.1999.0707
发表时间：
1999-04-22
影响因子：
4.7
作者：
Taylor, DJ;Crease, TJ;Brown, WM
通讯作者：
Brown, WM