World Federation of Pediatric Intensive Care and Critical Care Societies: Global Sepsis Initiative
World Federation of Pediatric Intensive Care and Critical Care Societies: Global Sepsis Initiative
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DOI：
10.1097/pcc.0b013e318207096c
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发表时间：
2011-09-01
影响因子：
4.1
通讯作者：
Latour, Jos
中科院分区：
文献类型：
--
作者：
Kissoon, Niranjan;Carcillo, Joseph A.;Latour, Jos
背景：据世界卫生组织估计，脓毒症占儿童每年死亡人数的60%-80%。适合资源稀缺和资源丰富环境的措施同样可以减少脓毒症死亡。在这方面，世界儿科重症监护和重症监护学会联合会董事会宣布全球儿科脓毒症倡议，一个旨在提高脓毒症儿童护理质量的质量改进计划。目的：宣布全球脓毒症倡议;证明所包括的一些捆绑包的合理性;并展示一些初步数据并鼓励参与。方法：全球儿科败血症倡议是作为一个基于网络的教育、演示和金字塔捆绑包/检查表工具开发的（http：//www.pediatricsepsis. org或http：//www. wfpiccs。org）。其中包括四类卫生资源。A类涉及非工业化环境，死亡率为< 5 yrs and >千分之三十。B类涉及非工业化环境，死亡率< 5岁，每1，000名儿童中< 30名。C类是一个发展中的工业化国家。在D类中，确定发达工业化国家，并提供单独的伴随行政和临床参数包或检查表质量改进建议，随着资源分配从A组增加到D组，分别需要更多的资源和任务。（A类，n = 34; B类，n = 12; C类，n = 84; D类，n = 231），并将质量保证报告发送给23个参与的国际中心。对C类和D类捆绑的分析表明，死亡率的降低与复苏的依从性相关（比值比，0.369; 95%置信区间，0.188-0.724; p < .0004）和重症监护室管理结论：世界儿科重症监护和重症监护学会联合会全球儿科败血症倡议在线。成功降低儿科死亡率和发病率，每年评估作为全球儿童保健质量改善的衡量标准，需要不断积极招募国际参与中心。请访问http://www.pediatricsepsis加入我们。http://www.wfpiccs.org（Pediatr Crit Care Med 2011; 12：494-503）
Background: According to World Health Organization estimates, sepsis accounts for 60%-80% of lost lives per year in childhood. Measures appropriate for resource-scarce and resource-abundant settings alike can reduce sepsis deaths. In this regard, the World Federation of Pediatric Intensive Care and Critical Care Societies Board of Directors announces the Global Pediatric Sepsis Initiative, a quality improvement program designed to improve quality of care for children with sepsis.Objectives: To announce the global sepsis initiative; to justify some of the bundles that are included; and to show some preliminary data and encourage participation.Methods: The Global Pediatric Sepsis Initiative is developed as a Web-based education, demonstration, and pyramid bundles/checklist tool (http://www.pediatricsepsis. org or http://www. wfpiccs. org). Four health resource categories are included. Category A involves a nonindustrialized setting with mortality rate < 5 yrs and > 30 of 1,000 children. Category B involves a nonindustrialized setting with mortality rate < 5 yrs and < 30 of 1,000 children. Category C involves a developing industrialized nation. In category D, developed industrialized nation are determined and separate accompanying administrative and clinical parameters bundles or checklist quality improvement recommendations are provided, requiring greater resources and tasks as resource allocation increased from groups A to D, respectively.Results: In the vanguard phase, data for 361 children (category A, n = 34; category B, n = 12; category C, n = 84; category D, n = 231) were successfully entered, and quality-assurance reports were sent to the 23 participating international centers. Analysis of bundles for categories C and D showed that reduction in mortality was associated with compliance with the resuscitation (odds ratio, 0.369; 95% confidence interval, 0.188-0.724; p < .0004) and intensive care unit management (odds ratio, 0.277; 95% confidence interval, 0.096-0.80) bundles.Conclusions: The World Federation of Pediatric Intensive Care and Critical Care Societies Global Pediatric Sepsis Initiative is online. Success in reducing pediatric mortality and morbidity, evaluated yearly as a measure of global child health care quality improvement, requires ongoing active recruitment of international participant centers. Please join us at http://www.pediatricsepsis. org or http://www.wfpiccs.org. (Pediatr Crit Care Med 2011; 12:494-503)