Interactive effects of physical work and carbon monoxide on cognitive task performance.
Interactive effects of physical work and carbon monoxide on cognitive task performance.
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体力劳动和一氧化碳对认知任务表现的交互影响。
DOI：
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发表时间：
1988
影响因子：
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通讯作者：
S. Horvath
中科院分区：
文献类型：
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作者：
D. Bunnell;S. Horvath
对11名男性和7名女性进行了一氧化碳暴露和之前的体力工作对认知能力的简单和交互影响的评估。三个水平的碳氧血红蛋白(HbCO)(0，7，10%)和三个工作负荷(休息，35%，60%最大摄氧量)交叉，导致每个受试者有9个重复测量条件。在注射CO后，受试者锻炼或休息50min，然后完成五项认知任务：人体空间处理、Sternberg记忆、Stroop文字-颜色干扰、视觉搜索和双轴跟踪，并有和没有次级数学任务。在给药后和完成最后一项任务后，再次评估碳氧血红蛋白水平。环境CO水平被设置为在每种情况下保持所需的HbCO水平。在顺序呈现的两个Stroop干扰任务中的第二个任务(使用相同的刺激，但指令相反)上的表现随着HbCO水平的增加而受损，这表明适应新反应集的能力降低。在视觉搜索成绩中，HbCO水平和运动水平之间存在交互作用：在休息条件下，随着HbCO水平的增加，视觉搜索成绩有所提高；相反，在60%的工作后，随着HbCO水平的增加，成绩会受到影响。HbCO升高对空间加工、短时记忆、简单反应时或精神运动追踪没有影响。
The simple and interactive effects of carbon monoxide (CO) exposure and prior physical work on cognitive performance were evaluated in 11 men and 7 women. Three levels of carboxyhemoglobin (HbCO) (0, 7, 10%) and three workloads (rest, 35%, 60% Vo2max) were crossed resulting in nine repeated measures conditions for each subject. Following bolus administration of CO, subjects exercised or rested for 50 min, then performed five cognitive tasks: Manikin spatial processing, Sternberg memory, Stroop word-color interference, visual search, and dual-axis tracking, with and without a secondary mathematics task. Carboxyhemoglobin levels were assessed after bolus administration and again following completion of the last task. Ambient CO levels were set to maintain the required HbCO levels in each condition. Performance on the second of two sequentially presented Stroop interference tasks (using identical stimuli but with instructions reversed) was impaired with increasing HbCO level, suggesting a reduced ability to adapt to a new response set. An interaction between HbCO level and exercise level was seen for visual search performance: in rest conditions, performance was improved with increasing HbCO level; by contrast, performance was impaired with increasing HbCO levels following 60% work. Elevated HbCO had no effect on spatial processing, short-term memory, simple reaction time, or psychomotor tracking.