Contaminated Handwashing Sinks as the Source of a Clonal Outbreak of KPC-2-Producing Klebsiella oxytoca on a Hematology Ward
Contaminated Handwashing Sinks as the Source of a Clonal Outbreak of KPC-2-Producing Klebsiella oxytoca on a Hematology Ward
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DOI：
10.1128/aac.04306-14
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发表时间：
2015-01-01
影响因子：
4.9
通讯作者：
Zollner-Schwetz, Ines
中科院分区：
文献类型：
--
作者：
Leitner, Eva;Zarfel, Gernot;Zollner-Schwetz, Ines
我们调查了水槽是否是产生肺炎克雷伯菌碳青霉烯酶（KPC）的催产克雷伯菌长期爆发的可能来源。在 4 个病房和药物室的水槽排水管中发现了 7 种耐碳青霉烯类产酸克雷伯菌。对患者和环境分离株的抗性基因和遗传相关性的调查显示，所有分离株均含有 bla(KPC-2) 和 bla(TEM-1) 基因，并且在遗传上无法区分。我们在此描述了由产生 KPC-2 的产酸克氏杆菌引起的克隆爆发，洗手池是可能的储存库。
We investigated sinks as possible sources of a prolonged Klebsiella pneumonia carbapenemase (KPC)-producing Klebsiella oxytoca outbreak. Seven carbapenem-resistant K. oxytoca isolates were identified in sink drains in 4 patient rooms and in the medication room. Investigations for resistance genes and genetic relatedness of patient and environmental isolates revealed that all the isolates harbored the bla(KPC-2) and bla(TEM-1) genes and were genetically indistinguishable. We describe here a clonal outbreak caused by KPC-2-producing K. oxytoca, and handwashing sinks were a possible reservoir.