Incremental validity of ERP correlates of self-referential processing in predicting emerging depressive symptoms in late childhood: Evidence from a community-dwelling sample.
Incremental validity of ERP correlates of self-referential processing in predicting emerging depressive symptoms in late childhood: Evidence from a community-dwelling sample.
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DOI：
10.1111/psyp.14382
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发表时间：
2023-07
期刊：
影响因子：
3.7
通讯作者：
Pan Liu;Jaron X Y Tan
中科院分区：
文献类型：
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作者：
Pan Liu;Jaron X Y Tan
抑郁症的自我参照处理（例如，自我图式反映了对积极的自我描述词的较浅处理和对消极的自我描述词的较深处理）是对抑郁症的既定认知脆弱性。在有抑郁症风险或临床抑郁症的青少年中观察到自我参照加工过程中事件相关电位（ERP）的变化。然而，没有研究已经检查了典型的风险青少年在童年后期出现抑郁症状，抑郁症的高风险时期与自我参照处理相关的ERP。目前还不清楚ERPs在多大程度上提供了预测症状的增量有效性，超越了自我参照处理任务的表现。65名社区儿童（38名女孩;平均年龄/标准差= 11.02/1.59岁）完成了自我指涉编码任务（SRET）与脑电图记录。儿童表现出更大的P2和更大的晚正电位（LPP）在响应于正SRET刺激与负刺激。分层回归显示，在积极的条件下，只有，包括ERP相关（P1，P2，LPP）和ERP和积极的SRET分数之间的相互作用增加了解释的变化，抑郁症状超越行为SRET性能。对积极词汇的LPP与较低的抑郁症状相关。P1和P2响应积极的话与积极的SRET分数，这样的关联积极的SRET分数和症状是显着的儿童与更大的P1，但较小的P2。我们提供了新的证据，支持ERP的增量有效性超越行为标记在预测儿童出现抑郁症状。我们的研究结果还强调了ERP活动在加强自我图式行为标记与抑郁结果之间的关联方面的调节作用。
Depressogenic self-referential processing (e.g., self-schemas reflecting shallower processing of positive, and deeper processing of negative, self-descriptive words) is an established cognitive vulnerability to depression. Alterations of event-related potentials (ERPs) during self-referential processing have been observed in adolescents with depression risk or clinical depression. However, no study has examined ERPs associated with self-referential processing in typical-risk youth with emerging depressive symptoms during late childhood, a high-risk period for depression. It is also unclear to what extent ERPs provide incremental validity in predicting symptoms beyond performance on self-referential processing tasks. Sixty-five community-dwelling children (38 girls; mean age/SD = 11.02/1.59 years) completed a self-referent encoding task (SRET) with EEG recorded. Children showed a larger P2 and a larger late positive potential (LPP) in response to positive SRET stimuli versus negative stimuli. Hierarchical regression showed that in the positive condition only, including ERP correlates (P1, P2, LPP) and interactions between the ERPs and positive SRET score increased the explained variation in depressive symptoms beyond behavioral SRET performance. The LPP in response to positive words was associated with lower depressive symptoms. The P1 and P2 in response to positive words interacted with positive SRET score, such that the association between positive SRET score and symptoms was significant in children with greater P1 but smaller P2. We provide novel evidence supporting the incremental validity of ERPs beyond behavioral makers in predicting emerging depressive symptoms in children. Our findings also highlight the moderating role of ERP activity in strengthening the association between behavioral markers of self-schemas and depressive outcomes.