DISSOLUTION RATES IN SURFACTANT SOLUTIONS UNDER STIRRED AND STATIC CONDITIONS
DISSOLUTION RATES IN SURFACTANT SOLUTIONS UNDER STIRRED AND STATIC CONDITIONS
复制标题
DOI：
10.1002/jps.2600570513
复制
发表时间：
1968-01-01
影响因子：
3.8
通讯作者：
WEINER, ND
中科院分区：
文献类型：
--
作者：
GIBALDI, M;FELDMAN, S;WEINER, ND
采用旋转圆盘法和静态圆盘法测定了苯甲酸在水和聚氧乙烯（23）十二烷基醚溶液中的溶出度。在搅拌和静态条件下的结果与Noyes - Whitney方程有很大的偏差。在表面活性剂溶液中的溶解速率远低于根据增溶数据预测的溶解速率。静态条件下，表面活性剂溶液与纯溶剂的溶解速率之比明显大于搅拌条件下的溶解速率之比，表明溶解机理可能发生了变化。探讨了溶解速率理论的某些方面来解释这一不寻常的现象。
The dissolution rate of benzoic acid was determined in water and solutions of polyoxyethylene (23) lauryl ether by the rotating disk and static disk methods. The results under stirred and static conditions substantially deviated from the Noyes‐Whitney equation. Dissolution rates in surfactant solutions were much less than anticipated on the basis of solubilization data. The ratios of dissolution rate in surfactant solution to that in pure solvent were found to be significantly greater under static conditions as compared to the ratios determined under stirred conditions, suggesting a possible change in dissolution mechanism. Certain aspects of dissolution rate theory are explored to explain this unusual phenomenon.